research Lupus erythematosus. What’s new?
This case report highlights the complexity of lupus erythematosus/lichen planus overlap syndrome, noting a high potential for progression to systemic lupus erythematosus.
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research PRESEPTAL CELLULITIS DUE TO IMPETIGO – A CASE REPORT OF UNCOMMON PRESENTATION IN PAKISTAN
This case study details a 30-year-old woman diagnosed with Lupus Vasculitis, presenting with symptoms like intermittent fever, joint pain, and respiratory issues, after tests revealed specific antibody patterns and reduced complement levels, leading to treatment with steroids, mycophenolate mofetil, and hydroxychloroquine.
research 062 A case of autoimmune facial swelling, weakness and sensorineuropathy with lower limb myositis
This case report highlights the overlap of Sjögren’s Syndrome and Systemic Lupus Erythematosus, noting major salivary gland enlargement and bilateral facial nerve involvement, which may better explain the patient's symptoms than lupus alone.
research LUPUS ERYTHEMATOSUS AND THE SKIN
This article reviews historical uses of the term "lupus" for various skin disorders but provides no new clinical findings.
research 12. Cancer
Some medications can improve skin conditions, while lifestyle factors like smoking and drinking may worsen them; treatments like monoclonal antibodies and imiquimod cream show promise for certain skin diseases.
research Lupus erythematosus: systemic and cutaneous manifestations
This article outlines manifestations of systemic lupus erythematosus, noting rapid joint symptom improvement with corticosteroids and antimalarial drug responsiveness for skin symptoms, and links anti-Ro with photosensitive rash and subacute lupus.
research Clinical and immunological manifestations in 151 SLE patients living in Dubai
This study found that Arabs with systemic lupus erythematosus in Dubai exhibit clinical features similar to SLE patients in other Arab and Western countries, with notable high prevalence of positive anti-Ro antibodies.
research Subacute cutaneous lupus erythematosus presenting as erythroderma
In this case report, a patient with subacute cutaneous lupus erythematosus and exfoliative erythroderma achieved complete remission with systemic corticosteroids and long-term hydroxychloroquine.
research Cutaneous lupus erythematosus induced by tislelizumab
In this case report, the authors concluded that cutaneous lupus erythematosus was induced by the PD-1 inhibitor tislelizumab during treatment for metastatic lung adenocarcinoma, despite initial remission and treatment adjustments.
research LUPUS VASCULITIS
In this case study, a 30-year-old woman with symptoms including fever, joint pain, and skin ulcers was diagnosed with Lupus Vasculitis and treated with steroids, mycophenolate mofetil, and hydroxychloroquine after tests showed positive anti-nuclear and anti-Ro antibodies and reduced serum complement levels.
research 127 Quality of life in patients with connective tissue diseases: results from the Lupus Extended Autoimmune Phenotype (LEAP) study
This study found that 59.7% of lupus patients self-reported alopecia, which was linked to anti-Ro antibody presence and cutaneous SLE symptoms but not to age, ethnicity, or medication.
research An Atypical Initial Manifestation of Systemic Lupus Erythematosus: Lupus Enteritis Accompanied by Intestinal Pseudo-Obstruction and Bilateral Hydronephroureter
In this case study, a 36-year-old female with severe lupus enteritis and intestinal pseudo-obstruction showed significant clinical improvement after treatment with intravenous methylprednisolone, hydroxychloroquine, and cyclophosphamide, highlighting the complexities and challenges in diagnosing and managing atypical lupus manifestations.
research Immune-mediated Coombs negative intravascular haemolysis in systemic lupus erythematosus (SLE)
This case report details a 27-year-old woman's diagnosis of systemic lupus erythematosus with immune-mediated intravascular haemolysis, which improved with steroid treatment.
research 125 Self reported alopecia in an ethnically diverse lupus cohort
This study found that self-reported alopecia was common in lupus patients, often characterized by changes in hair texture and volume, and was associated with anti-Ro antibodies and significant anxiety.
research Cutaneous lupus erythematosus. Diagnostic and therapeutic recommendations of the Polish Dermatological Society
This article presents diagnostic and therapeutic recommendations for cutaneous lupus erythematosus from the Polish Dermatological Society, but reports no new clinical findings.
research LUPUS AROUND THE WORLD Clinical and immunological manifestations in 151 SLE patients living in Dubai
This study suggests that Arabs with systemic lupus erythematosus in Dubai show similar clinical features to patients from other Arab and Western countries, with a notable prevalence of positive anti-Ro antibodies.
research Inaugural complete heart block in anti-SSA negative systemic lupus erythematosus: the diagnostic role of anti-PM-Scl 100 antibodies
This study reported a rare case of a young woman with complete heart block as the initial sign of systemic lupus erythematosus despite being negative for anti-SSA antibodies, highlighting the diagnostic utility of anti-PM-Scl 100 antibodies and nailfold capillaroscopy.
research 6. Phototherapy, Photomedicine, and Pigmentary Disorders
Stopping certain drugs can improve skin conditions, arsenicosis affects over half of a Bangladeshi village, males are more vulnerable, and certain treatments are effective for warts, acne, and psoriasis. Smoking and drinking are linked to psoriasis in men, a cream helps with a type of skin cancer, and low iron levels don't directly cause chronic hair loss in women.
research 353 Alopecia as a Symptom of Neonatal Lupus
This paper discusses Neonatal Lupus and notes that while alopecia is common in Systemic Lupus Erythematosus, it has not been reported in neonatal presentations; it presents no new clinical results.
research Frequency of neuro-psychiatric dysfunction in anti-SSA/SSB exposed children with and without neonatal lupus
This study found that parental reports of neuro-psychiatric disorders were higher in children exposed to maternal anti-Ro antibodies, yet these differences compared to controls were not statistically significant.
research 13. Wound Healing & Hair
Certain drugs can cause lupus, stopping these drugs is the main treatment. NB-UVB phototherapy clears psoriasis faster when applied three times a week. Monoclonal antibodies and oral pimecrolimus are effective in treating psoriasis. Smoking and drinking are linked to psoriasis in men. No direct link between low iron and hair loss was found. Vaccines are effective against genital herpes and human papillomavirus type 16.
research Pediatric Sjögren’s Syndrome: Focus on Ocular Involvement and Diagnostic Challenges
This retrospective study in pediatric patients with Sjögren's syndrome found consistent indications of tear film instability and identified systemic features like arthralgia, Raynaud's phenomenon, and frequent autoantibody positivity, underscoring the value of integrating clinical and ophthalmological assessments for early diagnosis.
research A Case Report of Male Systemic Lupus Erythematous with Antinuclear Antibodies-Negative: A Challenging Diagnosis
This case report highlights the challenge of diagnosing systemic lupus erythematosus in males and antinuclear antibody-negative patients, emphasizing the need for primary care doctors to maintain a high suspicion of the condition.
research Identification of tpo, tg, tshr and ana antibodies associated with thyroid disorders
In this study, researchers found varying levels of multiple autoantibody types among thyroid disorder patients, with 84.84% of those with immunological hypothyroidism reporting symptoms like weight gain and lethargy, whereas 81.81% of those with immune hyperthyroidism experienced hair loss.
research Skin involvement in systemic lupus erythematosus: a review article
This article reviews the classification and treatment of cutaneous manifestations in systemic lupus erythematosus, highlighting the importance of monitoring for disease progression and reports no new clinical results.
research Diagnostic dilemma: Multiple Autoimmune Syndrome versus incomplete Graham-Little-Piccardi-Lassueur Syndrome overlap mixed connective tissue disease
In this case study, a 53-year-old female with multiple autoimmune symptoms was diagnosed with Mixed Connective Tissue Disease, confirmed by specific antibodies, and showed significant clinical improvement after one year of treatment.
research 8. Pathology
Various skin conditions can be treated effectively with different methods, such as discontinuing certain drugs, using specific vaccines, applying creams, and changing lifestyle habits like smoking and drinking.
research LP-206 ANA-negative lupus presenting with segmental hyalinizing vasculitis and valvular heart disease – a rare case report
This case study reports clinical improvement and complete ulcer resolution in a 29-year-old woman with ANA-negative SLE treated for segmental hyalinizing vasculitis and valvular heart disease.
research Lupus erythematosus, thyroiditis, alopecia areata and vitiligo – A multiple autoimmune syndrome type 3 case presentation
This case study identified a 22-year-old patient with multiple autoimmune syndrome type 3, involving lupus erythematosus, autoimmune thyroiditis, alopecia areata, and vitiligo.
research CLINICAL SPECTRUM AND IMMUNOLOGICAL PROFILE OF PATIENTS WITH MIXED CONNECTIVE TISSUE DISEASE PRESENTING IN A TERTIARY CARE HOSPITAL
This study found that among mixed connective tissue disease patients in a tertiary care hospital in Pakistan, Raynaud phenomenon was the most common clinical feature, present in 80% of patients.