A Case of Autoimmune Facial Swelling, Weakness, and Sensorineuropathy with Lower Limb Myositis

May 2022 in “ Journal of Neurology Neurosurgery & Psychiatry ”

Sk Mamun Ur Rashid, Graham Warner

hair loss SLE systemic lupus erythematosus ANA anti-Ro antibodies anti-La antibodies myositis lymphocytic infiltration Sjogren's Syndrome primary Sjogren's Syndrome lupus ANA antibodies Ro antibodies La antibodies SS

TLDR The woman's facial symptoms are best explained by primary Sjögren’s Syndrome.

A 45-year-old woman with a 14-year history of myalgia, polyarthralgia, recurrent chest infections, oral ulcers, and hair loss was initially misdiagnosed with GCA/PMR but later identified as having SLE after developing new neurological symptoms. Despite normal initial imaging, further tests revealed bilateral sensory trigeminal neuropathy, asymmetric bifacial weakness, and myositis in the lower limbs. Immunology showed raised ESR, positive ANA, anti-Ro, and anti-La antibodies. The case highlights the overlap of symptoms between Sjögren’s Syndrome (SS) and Systemic Lupus Erythematosus (SLE), with major salivary gland enlargement and myositis being more common in primary SS but also present in this SLE case.

View this study on doi.org →

Discuss this study in the Community →

Related Community Posts Join

6 / 1000+ results

community Fin/dut increase in estrogen and autoimmune diseases

in Chat 6 upvotes 2 years ago

The conversation discusses the link between increased estrogen and autoimmune diseases, with a focus on avoiding soy and milk. It also mentions treatments like Minoxidil, finasteride, and RU58841 for hair loss.

community I don’t know what to do at this point

in Female 87 upvotes 6 months ago

A 21-year-old woman with female pattern baldness has tried minoxidil, red light therapy, and supplements without success. She is considering spironolactone and seeking medical advice.

community Hair Loss Journey so far and where to now (22yo)

in Is this regrowth? 1 upvotes 1 day ago

The user is experiencing hair loss and is using topical finasteride, rosemary oil, caffeine, microneedling, low-level laser therapy, scalp massages, ketoconazole shampoo, and various vitamins and supplements. They are concerned about potential gynecomastia and are considering using minoxidil if current treatments do not stop hair loss or promote regrowth.

community Hair Loss Worsened After Switching From Arimidex to Raloxifene, Despite Dutasteride

in General 178 upvotes 4 weeks ago

Switching from Arimidex to Raloxifene worsened hair loss despite using Dutasteride. The user added oral Minoxidil, dermastamping, and RU58841 to their regimen to address the issue.

community Hair Loss from Frequent Shampoo Changes Since 2020: Alternatives to Minoxidil?

in General 95 upvotes 1 month ago

The user experienced hair loss from overwashing and frequent product changes, seeking alternatives to Minoxidil due to having pets. Suggestions included using oral Minoxidil, ketoconazole shampoo, and maintaining a consistent hair care routine with gentle, sulfate-free products.

community Can Shampoo Treat Suspected Fungal Hair Loss?

in General 64 upvotes 1 month ago

Hair loss possibly caused by a fungal infection might be treated with antifungal shampoos or oral medications. If not fungal, treatments like minoxidil or finasteride may be necessary.

Related Research

1 / 1 results

research A Case of Autoimmune Facial Swelling, Weakness, and Sensorineuropathy with Lower Limb Myositis

May 2022 in “Journal of Neurology Neurosurgery & Psychiatry”

The woman's facial symptoms are best explained by primary Sjögren’s Syndrome.