Alopecia as a Symptom of Neonatal Lupus

    February 2012 in “ World Allergy Organization Journal
    Aura Pellizzeri, Durnes García, Joselit Torres, Mayra Visia Quiñones Martínez, Elianny Chavez, Diana Briceño
    Studysummary This paper discusses Neonatal Lupus and notes that while alopecia is common in Systemic Lupus Erythematosus, it has not been reported in neonatal presentations; it presents no new clinical results.
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    Neonatal Lupus, a rare disease in infants of mothers with Systemic Lupus Erythematosus (SLE) antibodies, was identified in a 1-month-old female presenting with persistent bloody diarrhea, dehydration, metabolic acidosis, and alopecia. The diagnosis was confirmed through positive Anti-Ro autoimmunity tests in both the infant and her mother. Initial treatment with methylprednisolone showed little improvement, but subsequent azathioprine treatment resulted in a good clinical response and reduced Anti-Ro values. This case highlighted the importance of clinical observation in diagnosing rare conditions, particularly when unusual symptoms like alopecia are present.
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