Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This abstract lists affiliations and states no financial interests but provides no research findings to summarize.

This article reviews different generations of synthetic retinoids for dermatological use, discussing their efficacy and significant side effects, but reports no new clinical results.

In this study, researchers developed a near-infrared-responsive nanoplatform that synergistically enhances chronic wound healing by accelerating mitochondrial restoration and immune modulation, leading to enhanced wound repair and high-quality healing in diabetic rat models.

This study reports a complex network of blood lncRNA and associated pathways in alopecia areata but suggests further research is needed for verification and understanding of these findings.

This study found that near-infrared microscopy can effectively detect complete medulla loss in scalp hair, which may serve as a potential biomarker for breast cancer diagnosis.

In this study, exosome-like nanoparticles derived from rose stem cell culture were found to enhance skin quality by increasing collagen production, reducing melanin and inflammation, and promoting cell migration in vitro, suggesting potential aesthetic applications.

This study developed dissolving microneedles using specific polymers for transdermal delivery of rizatriptan benzoate, demonstrating improved drug skin penetration and significant alleviation of migraine symptoms in vivo compared to passive diffusion, suggesting potential advantages over conventional treatment methods for acute migraine.

In this study, synthesized composite nanocarriers containing ribose and peptides demonstrated enhanced transdermal delivery, improved uptake by skin cells, promoted cell proliferation, enhanced antioxidant enzyme activities, and increased autophagy, suggesting a potential for more effective skin anti-aging treatments.

This audit of ritlecitinib prescribing for severe alopecia areata found that regional practices largely followed national guidelines but highlighted the need for better psychological assessments and more consistent use of SALT scoring to inform treatment continuation decisions after 36 weeks.

This article reviews the multifaceted roles of vitamin D beyond bone health and notes its potential involvement in reducing risks of certain cancers and autoimmune diseases, but it presents no new clinical results.

This review examines the potential of regulatory T cell-based therapies to transform treatment across various medical specialties by promoting immune tolerance and tissue repair, but it reports no new clinical results.

This review discusses the evolution and development of smart and multifunctional microneedles, highlighting their potential future importance in medical applications, but it reports no new experimental results.

This case report illustrates that pellagra can develop in patients with anorexia nervosa without typical signs of severe malnutrition, responding rapidly to nicotinamide and tryptophan therapy.

This review discusses the role of neural crest stem cell-like states in adult neural crest-derived tissues, suggesting they may contribute to tissue repair by generating new cell types and activating repair programs.

This case report suggests that Roux-en-Y gastric bypass may improve symptoms of non-classic adrenal hyperplasia related to 11-hydroxylase deficiency by reducing insulin resistance.

This review explores molecular targets for head and neck squamous cell carcinoma and discusses potential advancements in radiopharmaceuticals for targeted radionuclide therapy, reporting no new clinical results.

This study found that while micronutrient abnormalities are common among patients receiving home parenteral nutrition, serious consequences from these abnormalities are rare.

In this study, hair follicle stem cells from ND-GFP transgenic mice were observed to be pluripotent, effectively repairing peripheral nerve and spinal cord injuries in mouse models.

This study found that activation of the transcription factor Nrf2 in keratinocytes promotes wound healing in mice by expanding hair follicle stem cells, independent of changes in keratinocyte proliferation or migration.

In this study, researchers found that overexpression of LncRNA RP11-818O24.3 in hair follicle stem cells promotes their proliferation, self-renewal, and differentiation while inhibiting apoptosis through the FGF2-mediated PI3K/AKT signaling pathway, suggesting potential therapeutic applications for hair loss treatment.

This study found that selectively inactivating ribonucleotide excision repair in mouse epidermis leads to DNA damage, keratinocyte intraepithelial neoplasia, and squamous cell carcinoma, indicating a potential tumor-promoting mechanism related to compromised genome maintenance.

This research found that nod factor can induce root hair reorientation and gene expression in Medicago truncatula with as little as a single molecule, implicating heterotrimeric G-protein signaling in this process.

This study observed that decreased nucleolar organizing region protein synthesis in hair root cells is correlated with hair loss in humans.

This review discusses keratin disorders and potential RNA interference therapeutics, reporting no new clinical findings but highlighting the promise of siRNA for future treatments.

This study reviewed competing endogenous RNA networks related to skin aging and wound healing, finding mechanisms like UVB-induced senescence and photoaging, as well as potential therapeutic targets for improving skin health and recovery.

In this study, researchers used single-cell RNA sequencing to identify seven cell types, including distinct steroidogenic and immune cells, in the tumor microenvironment of a case of ovarian SCT-NOS, providing insights into its cellular heterogeneity and molecular mechanisms related to hyperandrogenism.

In this study, researchers developed a novel computational framework using deep reinforcement learning to identify strategies for cellular reprogramming in gene regulatory networks, showing its effectiveness in a model of immune response against infection.

This study reports that the near-naked hairless mutation in mice is not an allele of the Hairless gene but may involve a mutation in a linked gene or a regulatory mutation.

This study reports that miR-302 promotes pluripotency by inhibiting NR2F2 and indirectly regulating OCT4 in stem cells, enhancing reprogramming efficiency when added to traditional factors.