Rizatriptan Benzoate-Loaded Dissolving Microneedle Patch for Management of Acute Migraine Therapy

    Chao Zhong, Xiufeng Zhang, Yanfang Sun … Guohua Jiang
    Studysummary This study developed dissolving microneedles using specific polymers for transdermal delivery of rizatriptan benzoate, demonstrating improved drug skin penetration and significant alleviation of migraine symptoms in vivo compared to passive diffusion, suggesting potential advantages over conventional treatment methods for acute migraine.
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