July 1995 in “Journal of Dermatological Science” Cyclosporine starts hair growth faster, while minoxidil makes it last longer.
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February 2009 in “Nature Reviews Molecular Cell Biology” Skin stem cells are crucial for maintaining and repairing the skin and hair, using a complex mix of signals to do so.
383 citations,
February 2011 in “Nature Reviews Genetics” DNA profiling in forensics has improved, but predicting physical traits and ancestry from DNA has limitations and requires ethical consideration.
351 citations,
February 2010 in “Nature Cell Biology” Basal cell carcinoma mostly starts from cells in the upper skin layers, not hair follicle stem cells.
260 citations,
January 2019 in “Pharmaceutics” Niosomes are a promising, stable, and cost-effective drug delivery system with potential for improved targeting and safety.
237 citations,
February 2016 in “Science Translational Medicine” The timing of when the gene Bmal1 is active affects aging and survival, with its absence during development, not adulthood, leading to premature aging.
192 citations,
March 2017 in “Cell host & microbe” Hair follicle development and microbes help regulatory T cells gather in newborn skin.
191 citations,
September 2011 in “Cell stem cell” Hair follicle stem cells use specific chromatin changes to control their growth and differentiation.
182 citations,
August 2016 in “Development” ATP-dependent chromatin-remodeling complexes are crucial for gene regulation, cell differentiation, and organ development in mammals.
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November 2016 in “Cell stem cell” Different types of skin cells have unique genetic markers that affect how likely they are to spread cancer.
165 citations,
February 1994 in “Fertility and Sterility” Flutamide is more effective and has fewer side effects than spironolactone for treating hirsutism.
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July 2015 in “Clinical, Cosmetic and Investigational Dermatology” Eating less sugar, milk, and saturated fats and more vegetables and fish may help treat and prevent acne.
134 citations,
January 2010 in “Biomedical research” Low oxygen conditions increase the hair-growing effects of substances from fat-derived stem cells by boosting growth factor release.
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February 2018 in “Nature Reviews Genetics” Stem cell plasticity is crucial for wound healing but can also contribute to cancer development.
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October 2013 in “Trends in Genetics” The AUTS2 gene is linked to neurological disorders and may affect human brain development and cognition.
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March 2014 in “BioEssays” We need more research to better understand human hair follicle stem cells for improved treatments for hair loss and skin cancer.
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May 2003 in “Endocrinology” Lampreys have a functional vitamin D receptor that may help detoxify harmful substances.
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September 2016 in “Reviews in Endocrine and Metabolic Disorders” The sebaceous gland has more roles than just producing sebum and contributing to acne, and new research could lead to better skin disease treatments.
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May 2012 in “British Journal of Dermatology” Androgens block hair growth by disrupting cell signals; targeting GSK-3 may help treat hair loss.
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April 2003 in “Proceedings of the National Academy of Sciences of the United States of America” Fatty acid transport protein 4 is essential for skin and hair development.
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September 2015 in “Journal of Lipid Research” Skin fat helps with body temperature control and has other active roles in health.
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November 2017 in “Journal of Cellular Physiology” The Wnt/β-catenin pathway is important for tissue development and has potential in regenerative medicine, but requires more research for therapeutic use.
88 citations,
May 2005 in “Journal of Dermatological Science” Versican, a protein, is less present in thinning hair follicles and this decrease might contribute to common hair loss in men.
87 citations,
July 2009 in “The journal of investigative dermatology/Journal of investigative dermatology” Human beard hair medulla contains a unique and complex mix of keratins not found in other human tissues.
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October 2015 in “Proceedings of the National Academy of Sciences of the United States of America” NF-κB is crucial for zebrafish heart repair, affecting heart cell growth and repair processes.
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March 2010 in “Infectious Disease Clinics of North America” The document concludes that rapid identification, isolation, and strict infection control are crucial to manage SARS outbreaks.
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October 2002 in “Journal of Dermatological Science” Sophora flavescens extract may help hair grow by affecting growth factors and blocking a hair-related enzyme.
70 citations,
February 2015 in “Expert Opinion on Drug Discovery” Topical drugs and near-infrared light therapy show potential for treating alopecia.
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August 2007 in “American Journal of Pathology” Overexpressing the mineralocorticoid receptor in mouse skin causes skin thinning, early skin barrier development, eye issues, and hair loss.
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December 2013 in “Nature Cell Biology” Inactive hair follicle stem cells help prevent skin cancer.