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CTP-543 is generally safe for treating alopecia areata.

Raltegravir may cause hair loss in some patients.

In this study, researchers found that during late pregnancy, neuroactive steroid fluctuations increase the number of extrasynaptic GABAA receptors in rat hippocampal cells.

This study discusses the difficulties in interpreting and communicating the association of 5α-reductase inhibitors with impaired libido and erectile dysfunction in men with benign prostatic hyperplasia due to the use of odds ratios instead of relative risks.

This study found that chemical lumbar sympathectomy with 5% phenol effectively treated idiopathic livedo reticularis in most patients, offering a potential long-lasting solution with repeatable efficacy upon recurrence.

This study found that in male rats, hesperidin co-administration ameliorated finasteride-induced testicular toxicity by reducing oxidative stress and improving antioxidant status, sperm parameters, and enzyme activity compared to finasteride treatment alone.

This report from a consensus meeting concluded that while 5-alpha reductase inhibitors are beneficial for BPH treatment and prostate cancer risk reduction, their role in clinical practice should be more widely integrated into prostate management guidelines.

In an animal study, researchers found that a hair tonic containing a 1:1 ratio of kelor and rambutan leaf extracts led to similar hair growth in rabbits compared to a minoxidil control, with average hair lengths of 3 cm versus 2.025 cm, respectively.

Finasteride significantly reduced tics and obsessive-compulsive symptoms in Tourette syndrome patients.

This article discusses lifestyle drugs, their subjective value, and the challenges in determining who should pay for them, highlighting the need for consensus on priorities and strategies.

Finasteride use in young people may increase risk of suicidal thoughts and mental health issues.

This review discusses the evolution of Cereblon ligands in PROTAC technology, highlighting chemical innovations that may enhance drug-likeness and applicability in protein degradation, while noting challenges and future research directions.

This case study highlights the importance of early diagnosis and treatment of acneiform eruptions associated with erlotinib in a 67-year-old male patient with non-small cell lung cancer to ensure patient compliance.

This study found that combining dibenyline and finasteride for symptomatic BPH treatment offered modest improvements with fewer additional side effects compared to each drug alone.

This study found that letrozole, an aromatase inhibitor, reduced the incidence and severity of PTZ-induced kindling seizures in mice, potentially due to its effects on 17β-estradiol and neurosteroid synthesis.

This article discusses the rationale, design, major findings, and updated objectives and methods of the ongoing Rotterdam Study on various diseases, without reporting new research results.

This review examines the placebo response in conditions such as allergies and weight loss, highlighting its significance in both conventional and alternative medicine randomized trials, without reporting any new results.

This study found that the binding of finasteride to the enzyme 5a-reductase occurs at a slower rate than previously assumed, complicating the estimation of its real inhibitory constant.

The article concludes that recent legal rulings have strengthened the protection of pharmaceutical patents against generic competition.

This study discusses levetiracetam's role as an alternative treatment for idiopathic generalized epilepsies, highlighting its potential effectiveness, especially for patients unsuitable for valproate.

This review details the process and advantages of drug repurposing, highlighting its potential as a cost-effective and expedited alternative to traditional drug development while summarizing various strategies and successful examples, and exploring related regulatory challenges.

This study observed that patients undergoing indinavir/ritonavir therapy for HIV-1 frequently experienced reversible alopecia, likely due to retinoid-like effects, but these were independent of other retinoid-like skin manifestations.

This study investigated various synthesized 5-reductase inhibitors and found that compound 6 had the highest anti-androgenic activity and receptor affinity compared to finasteride, showing potential due to its improved efficacy and bioavailability for further research in treating lower urinary tract symptoms.

This study observed that JAK inhibitors were effective and safe for treating alopecia totalis and universalis, with improved response rates seen most with ritlecitinib and tofacitinib by week 24.

This article reviews the synthesis and properties of isotretinoin, tazarotene, minoxidil, and finasteride, and reports no new findings.

This abstract provides information on various oral contraceptives, their potential hazardous interactions, and possible side effects, without presenting new research findings.

This study found that patients with rheumatoid arthritis taking tofacitinib had higher rates of serious adverse events compared to those with alopecia areata, highlighting the need for careful assessment when using it off-label for alopecia areata.

This study concluded that alpha(1)-adrenoceptor antagonists are more effective than finasteride in the short term for reducing symptoms of lower urinary tract symptoms associated with benign prostatic hyperplasia.