Erlotinib Induced Acneiform Eruption: A Case Report
December 2013
in “
Cumhuriyet Tıp Dergisi/Cumhuriyet Üniversitesi Tıp Fakültesi dergisi
”
New to Salicylic acid? There is a guide in the encyclopedia. Read the guide → Studysummary This case study highlights the importance of early diagnosis and treatment of acneiform eruptions associated with erlotinib in a 67-year-old male patient with non-small cell lung cancer to ensure patient compliance. Our plain-language summary of this paper — not a Tressless recommendation.
Erlotinib, an epidermal growth factor inhibitor used for non-small cell lung cancer, was reported to cause acneiform eruptions as a common skin-related side effect. This case report detailed a 67-year-old male who developed such eruptions on his face following erlotinib treatment. The condition was attributed to a disturbance in the balance between differentiation and maturation of skin cells. Treatments like topical metronidazole, clindamycin, salicylic acid, and tetracycline were suggested, and in severe cases, adjusting the erlotinib dosage or delaying treatment was recommended. Early diagnosis and management of these skin lesions were emphasized as crucial for maintaining patient compliance with erlotinib therapy.
