research Novel Therapies for Alopecia Areata: The Era of Rational Drug Development
New targeted therapies for hair loss from alopecia areata show promise, with personalized treatment expected in the future.
Search
for
Sort by
Research
480-510 / 1000+ results 
research Persistent Poor Metabolic Profile in Postmenopausal Women With Ovarian Hyperandrogenism After Testosterone Level Normalization
Postmenopausal women with hyperandrogenism didn't have better metabolic health even after their testosterone levels became normal.
research Essential Role of STAT3 Signaling in Hair Follicle Homeostasis
STAT3 signaling is important for healthy skin and hair follicles, and its disruption can lead to skin conditions like atopic dermatitis.
research Hair Growth Promoting Effects of 650 nm Red Light Stimulation on Human Hair Follicles and Study of Its Mechanisms via RNA Sequencing Transcriptome Analysis
650 nm red light helps hair grow and prevents hair loss by affecting certain genes and biological processes.
research PLCD1 and Pilar Cysts
The research linked PLCD1 gene variants to the development of trichilemmal cysts.
research Clinical Patterns of Hair Loss in Men
The document concludes that more research is needed to understand hair loss in men and to find new treatments.
research Genomic and Transcriptomic Characterization of Atypical Recurrent Flank Alopecia in the Cesky Fousek
The study found that the hair loss condition in Cesky Fousek dogs is influenced by multiple genes affecting skin and muscle structure, fat metabolism, and immunity.
research Clinical and Genetic Aspects of Alopecia Areata: A Cutting Edge Review
Hair loss from Alopecia Areata is caused by both genes and environment, with several treatments available but challenges in cost and relapse remain.
research Insights Into Male Androgenetic Alopecia Using Comparative Transcriptome Profiling: Hypoxia-Inducible Factor-1 and Wnt/Beta-Catenin Signalling Pathways
Targeting specific genes in certain pathways may help treat male pattern baldness.
research Androgenic Alopecia: Cross-Talk Between Cell Signal Transduction Pathways
Hair loss in Androgenetic alopecia (AGA) is due to altered cell sensitivity to hormones, not increased hormone levels. Hair growth periods shorten over time, causing hair to become thinner and shorter. This is linked to miscommunication between cell pathways in hair follicles. There's also a change in gene expression related to blood vessels and cell growth in balding hair follicles. The exact molecular causes of AGA are still unclear.
research Hair Biology and Care Product Ingredients from Marine Organisms
Marine-derived ingredients show potential for hair health but need more human trials to confirm effectiveness.
research Molecular Mechanisms of Y Chromosome Loss and UTY Gene Activity
Loss of the Y chromosome and UTY gene activity increases cancer risk in men.
research Whole-Genome Resequencing Reveals Selection Signal Related to Sheep Wool Fineness
Genes linked to wool fineness in sheep have been identified.
research Spectrum of Clinical Manifestations of SLE Patients from India and Its Correlation with KIR Gene Polymorphism
Certain KIR genes in Indian SLE patients are linked to disease severity and could be biomarkers.
research Autoimmune Diseases and Acquired Von Willebrand Disease in Two Cases of Progeria
Premature aging increases the risk of immune problems and autoimmune diseases.
research Definition Criteria and Diagnostic Assessments for Polycystic Ovary Syndrome
The document concludes that accurate diagnosis and management of PCOS are crucial due to its associated health risks.
research Assessment of Catalase Intrinsic Emissions of Electromagnetic Fields as a Probable Cause in Cancerogenesis from Consumption of Red and Processed Meat
Catalase in processed meats may emit electromagnetic fields that increase cancer risk.
research Androgen Treatment in Women
Testosterone therapy can help with androgen deficiency in women but should be used with caution and monitoring due to potential risks.
research Early Onset Androgenic Alopecia as the Male Phenotypic Equivalent of Polycystic Ovarian Syndrome Is Associated with High Oxidative Stress
Men with early hair loss may have higher health risks similar to women with PCOS.
research Brain And Muscle Arnt-Like Protein-1 (BMAL1) Controls Circadian Cell Proliferation And Susceptibility To UVB-Induced DNA Damage In The Epidermis
BMAL1 controls skin cell growth and UV damage risk, peaking at night.
research EDA2R Is Associated With Androgenetic Alopecia
EDA2R gene linked to hair loss.
research Beta-Caryophyllene Enhances Wound Healing Through Multiple Routes
Beta-caryophyllene helps improve wound healing in mice, especially in females.
research Surrogate End-Points or Primary Outcomes in Clinical Trials in Women with Polycystic Ovary Syndrome?
The document suggests that clinical trials for PCOS should focus on meaningful primary outcomes like live birth rates, rather than less reliable surrogate markers.
research Homozygous ALOXE3 Nonsense Variant Identified in a Patient with Non-Bullous Congenital Ichthyosiform Erythroderma Complicated by Superimposed Bullous Majocchi’s Granuloma: The Consequences of Skin Barrier Dysfunction
A specific gene variant causes severe skin issues and increases infection risk, requiring careful medical monitoring.
research Association of Atopic Dermatitis With Autoimmune Diseases: A Bidirectional and Multivariable Two-Sample Mendelian Randomization Study
Atopic dermatitis increases the risk of some autoimmune diseases.
research Male Equivalent Polycystic Ovarian Syndrome: Hormonal, Metabolic, and Clinical Aspects
Men with hormonal imbalances similar to PCOS may have increased risk of metabolic and heart diseases.
research Impact of Androgen Deprivation Therapy on Mortality of Prostate Cancer Patients with COVID-19: A Propensity Score-Based Analysis
Androgen deprivation therapy doesn't lower the risk of death from COVID-19 in prostate cancer patients.
research Applications of Ultrasound-Mediated Gene Delivery in Regenerative Medicine
Ultrasound can help deliver genes to cells to stimulate tissue regeneration and enhance hair growth, but more research is needed to perfect the method.
research Beta-Caryophyllene Enhances Wound Healing Through Multiple Routes
Beta-caryophyllene, found in essential oils, helps wounds heal better in multiple ways.
research A Study of the Association of Premature Androgenetic Alopecia with Metabolic Syndrome and Coronary Artery Disease
Premature hair loss doesn't increase the risk of metabolic syndrome.