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This study revealed that Vav2 and Vav3 play roles in regulating hair follicle bulge stem cells in normal conditions and cancer stem cell activation and remodeling in mice.

This study used developing mouse hair follicles to explore early epithelial bud formation, finding that the Rho GTPase regulator ARHGEF3 plays a crucial role in regulating cell fate and cadherin patterning, with knockouts showing disrupted morphology and increased straight hair follicle growth.

This study found that a catalytically active version of Vav2 significantly altered gene expression patterns in hair follicle stem cells in mice, with these changes varying over the animals' lifespans.

This study found that the ablation of Esrp1 and Esrp2 disrupts epithelial tight junctions by affecting Arhgef11 isoform expressions, highlighting a potential mechanistic link between splicing alterations and epithelial barrier defects.

In this study, the authors found that inhibiting Cdc42 activity with CASIN restored hair follicle stem cell function and hair growth in aged mice, suggesting potential for treating aging-related hair regeneration issues.

This study found that treating aged mice with the Cdc42 inhibitor CASIN restored hair follicle stem cell functionality and improved hair regeneration by inducing anagen onset and increasing anagen skin areas.

This review discusses the role of lysophosphatidic acid in skin physiology and pathology, highlighting its significance in processes like wound healing and hair follicle development, but reports no new clinical findings.

This review discusses the role of PIN-FORMED 2 and related signaling pathways in root hair growth regulation and reports no new experimental findings.

This study found that ILK/ELMO2 complexes in epidermal keratinocytes are selectively activated by epidermal growth factor to induce cell migration, unlike with other growth factors.

This study suggests that CD151-integrin complexes inhibit epithelial cell migration, and that disruption of these complexes enhances migration, regulated by Rho GTPase activation differences on distinct laminins.

This study found that low temperatures and nitrogen deficiency trigger root hair elongation through a molecular mechanism involving the receptor kinase FERONIA and the TOR Complex 1.

This study reports that localized Rho GTPase activity and ROS production play a critical role in polarized growth and movement in both migrating endothelial cells and developing plant root hairs.

This study found that Par3 plays a crucial role in maintaining epidermal homeostasis by regulating Rho/actomyosin contractility and ensuring mitotic accuracy, with potential implications for other self-renewing epithelia.

This study found that deleting the CD98hc protein in mouse skin impairs wound healing and homeostasis, resembling aging effects, due to disrupted integrin signaling pathways.

This review examines PAK4 signaling pathways in prostate cancer, Parkinson's disease, and melanogenesis, focusing on the potential role of the PAK4-CREB axis, without reporting new clinical results.

This study found that dysregulation of the folliculin-p0071 interaction may lead to changes in cell adhesion and signaling, contributing to conditions like emphysema and renal cell carcinoma.

This research suggests that the barley protein RACB supports cell polarity functions rather than interfering with immunity, as it aids nucleus positioning during fungal attack rather than affecting early immune responses.

This study observed that exosomes from adipose mesenchymal stem cells overexpressing hepatocyte growth factor significantly improved liver function and reduced fibrosis in mice with experimentally induced liver injury.

This study found that overexpressing the gene Thymosin β4 (Tβ4) can promote the growth and development of secondary hair follicle dermal papilla cells in cashmere goats, suggesting its potential as a target for increasing cashmere production.

This study found that ARHGEF3 is crucial for hair follicle development in mice, as its absence leads to defects in placode compaction and impaired follicle downgrowth, highlighting its role in regulating cell shape rearrangements during embryogenesis.

This study provides evidence that five Hyp-O-GALT genes are crucial for AGP galactosylation and that AGP glycans are vital for various aspects of plant growth and development.

This review discusses melanocyte development, emphasizing the plasticity of melanoblasts and the role of both intrinsic and extracellular signals in their differentiation and migration, with no new clinical results reported.

AGD1 is important for root hair development in Arabidopsis, working with phosphoinositide signaling and the actin cytoskeleton.

This review presents updated tables of mouse mutants with hair growth abnormalities to aid in understanding the molecular mechanisms of human hair disorders, but reports no new clinical results.

This study identified two significant genomic regions potentially involved in hair development and growth in Casertana pigs, highlighting FOXN3 and ARHGEF10 as candidate genes associated with a hairless phenotype.

In this narrative review, researchers outlined the role of T cells in the autoimmune pathogenesis of alopecia areata and highlighted ongoing research into therapeutic pathways, beyond current JAK inhibitors, aimed at developing new treatments for the disease.

This review discusses the dual role of apoptotic vesicles in disease and therapy, emphasizing their potential in cancer treatment and tissue regeneration, but reports no new results.

This study found that the NHD domain, but not the PHD domain, of hPygo2 is crucial for Wnt-independent growth of ovarian cancer cells, and identified a key interaction with Treacle protein involved in ribosomal biogenesis.

This review explores how adult skin epithelia preserve stem cell populations for hair follicle regeneration and wound healing, but reports no new experimental results.

This review discusses manipulating the stem cell niche as a strategy in regenerative medicine to repair damaged tissues, highlighting the potential benefits and challenges but reporting no new results.