Identification of Pygopus 2 as a Component of the Ribosomal RNA Transcription Complex in Cancer
January 2008
in “
Memorial University Research Repository (Memorial University)
”
Studysummary This study found that the NHD domain, but not the PHD domain, of hPygo2 is crucial for Wnt-independent growth of ovarian cancer cells, and identified a key interaction with Treacle protein involved in ribosomal biogenesis.
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