Apobds: A Paradigm Shift From Cellular Debris To Therapeutic Vehicles
July 2025
in “
Frontiers in Endocrinology
”
Studysummary This review discusses the dual role of apoptotic vesicles in disease and therapy, emphasizing their potential in cancer treatment and tissue regeneration, but reports no new results. Our plain-language summary of this paper — not a Tressless recommendation.
Apoptotic bodies (ApoBDs), once considered cellular debris, are now recognized as therapeutic vehicles with dual roles in disease promotion and treatment. This review discusses their formation, functions, and potential applications in cancer therapy, immune modulation, and tissue regeneration. ApoBDs contain bioactive molecules that can drive tumor growth and metastasis but also aid in tissue repair. The paper highlights the transformative potential of ApoBDs in modern medicine and addresses the challenges and future directions for their research and clinical use.
