July 2021 in “IntechOpen eBooks” This review discusses the potential of ginseng and its metabolites for treating hair loss and reports no new clinical findings.
16 citations
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April 2021 in “Frontiers in Cell and Developmental Biology” This review discusses human hair follicle development and highlights the potential of creating human in vitro models and skin substitutes with hair follicles, reporting no new clinical results.
2 citations
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October 2021 in “Experimental Cell Research” This study found that injectable platelet-rich fibrin (i-PRF) enhances hair follicle regeneration in vitro by promoting human dermal papilla cell proliferation, migration, and trichogenic inductivity, with varying effects depending on concentration.
This study reported that autogenic hair follicle transplantation provided good cosmetic results and improved quality of life for patients with post-irradiation alopecia, despite delayed hair regrowth due to blood supply deficits.
March 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This source describes a collection of geometric medicine formulations aimed at comprehensive hair restoration and permanent hair removal, with claimed simulation results indicating complete baldness reversal and effective hair removal, but results are sourced from theoretical and simulation-based findings without reported clinical trials.
1 citations
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March 2013 in “Hair transplant forum international” This review discusses the historical significance and applications of tissue expansion in reconstructive surgery but provides no new clinical data on its use in hair restorative procedures.
19 citations
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October 1988 in “Clinics in dermatology” This article discusses potential roles for retinoids in hair regrowth and proposes future studies, reporting no new experimental results.
May 2012 in “F1000Research” This research consisted of a Phase I/II study on androgenetic alopecia where male participants received intradermal injections of HSC, with hair growth efficacy assessed through Trichoscan imaging, although no new clinical results are reported.
January 2025 in “SSRN Electronic Journal”
March 2025 in “International Journal of Molecular Sciences” Veratric Acid may help promote hair growth and reduce hair loss.
8 citations
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October 2017 in “Dermatology practical & conceptual” This study found that a spermidine-based nutritional supplement increased the number of anagen phase hair follicles in healthy humans, suggesting potential benefits for hair loss conditions.
October 2015 in “CRC Press eBooks” This article reviews the concept of using cell therapy for hair loss treatment, emphasizing the ongoing development of methods to create and implant hair follicles in vitro but reports no new findings.
3 citations
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May 2019 in “Medical Hypotheses” This article discusses the potential of using vitrified hair follicles from younger men with a family history of male pattern baldness to increase donor availability for future hair transplantation, and reports no clinical results.
November 2023 in “Materials Today Bio” In this study, researchers developed a novel temperature-sensitive biopolymer-based drug delivery system that enhanced the transdermal delivery of ISX9, a neurogenesis inducer, resulting in more effective hair follicle regrowth and signal pathway activation in vivo compared to traditional topical application.
The research examined Crown-X, a novel formulation containing Menstrual Stem Cells, and found that it promoted significant proliferation of human dermal papilla cells, suggesting its potential as a non-invasive treatment for male pattern baldness. Future clinical trials are necessary to confirm its efficacy.
July 2026 in “Journal of the American Academy of Dermatology”
1 citations
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May 2017 in “Hair transplant forum international” This paper discusses the recent online debate over the use of PRP in hair restoration but provides no new findings.
January 2020 in “Journal of Genetics and Gene Therapy” This article discusses the potential use of human hair follicular stem cells combined with platelet-rich plasma for androgenetic alopecia, focusing on the regenerative processes involved, but reports no new clinical results.
August 2023 in “Zenodo (CERN European Organization for Nuclear Research)”
June 2002 in “Seminars in Cutaneous Medicine and Surgery” Hair transplantation has improved to more natural-looking results and is complemented by effective non-surgical treatments, with ongoing research into hair follicle cloning.
January 2022 in “Stem cell biology and regenerative medicine” This review discusses strategies for hair follicle regeneration using tissue engineering and reports no new clinical results; the authors highlight potential future directions for promoting hair neoformation.
1 citations
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November 2022 in “International journal of trichology” In this case study, a 25-year-old female with premature hair graying achieved over 90% conversion of gray hair to black hair after 5 months of treatment with a topical peptide solution and hair supplements.
June 2026 in “International Journal of Pharmaceutics”
16 citations
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January 2018 in “Biochemical and Biophysical Research Communications” In this study, researchers established five new immortalized human dermal papilla cell lines from a male with androgenetic alopecia, which may serve as valuable tools for hair research.
August 2026 in “Current Stem Cell Research & Therapy” This study found that extracellular vesicles from mesenchymal and outer root sheath stem cells may inhibit hair follicle stem cell apoptosis, suggesting potential therapeutic benefits for hair loss treatments.
September 2017 in “Journal of Investigative Dermatology” In this study, a topical combination of Stemoxydine® and Resveratrol significantly increased hair density in women with female pattern hair loss after 12 weeks of use.
January 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This document from Xenofolix Hair Transplantation discusses modern approaches to hair restoration, emphasizing diagnosis-led treatments, donor area management, and the integration of both surgical and non-surgical methods for long-term success, while guiding individuals on selecting quality care and ethical hair transplant clinics in Kochi.
January 1992 in “Biology of the Cell” Retinoic acid receptors are important for hair follicle development.
38 citations
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August 1973 in “Journal of Investigative Dermatology”
October 2023 in “Journal of the Endocrine Society” In this study, estetrol (E4) treatment was associated with increased hair growth in ex vivo human hair follicles, suggesting its potential as a treatment for hair loss disorders.