Follicular Cell Implantation: Research Update on Hair Cloning

October 2015 in “ CRC Press eBooks ”

Jerry E. Cooley

follicular cell implantation hair cloning cell therapy epidermal cells mesenchymal cells hair growth follicular neogenesis hair follicles in vitro alopecia autologous cell therapy keratinocytes bulge stem cells stem cells

TLDR Hair cloning for hair loss is not yet a practical solution.

Follicular cell implantation, or "hair cloning," was anticipated to become a practical solution for hair loss, but it remained far from clinical reality. The concept of using cell therapy for hair loss was based on the dynamic interaction between epidermal and mesenchymal cells in hair growth. Research focused on follicular neogenesis models aimed to create hair follicles in vitro for implantation into alopecia-affected areas. Autologous cell therapy would require adult keratinocytes, especially those with "bulge" stem cell properties.

View this study on taylorfrancis.com →

Discuss this study in the Community →

Research cited in this study

1 / 1 results

research Follicular Cell Implantation: An Update on Hair Follicle Cloning

15 citations, May 2004 in “Facial Plastic Surgery Clinics of North America”

The document concludes that while "hair follicle cloning" shows promise for unlimited donor hair, it faces challenges with consistency and safety in humans.

Related Community Posts Join

6 / 171 results

community The MPB itch aka DHT itch is very real.

in Chat 9 upvotes 1 year ago

Hair loss itch is caused by DHT attacking follicles and stimulating nerves. Finasteride users who respond well don't experience this itch.

community New Treatments, and a Huge Group Buy with Lots of Research

in Research/Science 109 upvotes 1 year ago

A user is organizing a group buy for various compounds aimed at reversing hair loss and gray hair, and improving brain health and fat loss. The user has developed a treatment plan based on extensive research and is inviting others to participate, with the option to choose only the compounds they need.

community HairClone developing cell replacement treatments for Hair Loss

6 upvotes 6 years ago

HairClone is developing cell replacement treatments to rejuvenate and generate hair follicles, and has launched a crowdfunding campaign. A user expressed skepticism about the need for crowdfunding.

community New and Interesting HairLoss Studies/Papers/Reviews

in Treatment 42 upvotes 4 years ago

Hair loss treatments discussed include Dutasteride with Ketoconazole, tissue engineering strategies, and androgenetic alopecia therapies. Massage doubles follicular retention, improving treatment effectiveness.

community Verteporfin day 84 update - donor hair regeneration human trials

in Research/Science 33 upvotes 2 years ago

A human trial involving verteporfin for hair regeneration, with the results showing some regrowth of 1-2 hairs in an area where a follicular unit was extracted. The conversation also suggested that future studies should involve higher doses and more frequent injections.

community Clearing the air on how non-surgical treatments really work

18 upvotes 5 years ago

Treatments for hair loss, including finasteride, dutasteride, minoxidil, ketoconazole, microneedling, and low level laser light therapy, which aim to reduce DHT production, increase cell absorption and blood flow, and stimulate epidermal stem cells. It also stresses the importance of patience when using these treatments.

Related Research

1 / 1 results

research The Art of Mixing Follicular Units and Follicular Groupings in Hair Restoration Surgery

June 2004 in “Dermatologic Surgery”

Mixing different sizes of hair follicles during hair restoration surgery can give excellent results, save time, and cause less damage.