Hair Transplantation: State of the Art

    June 2002 in “ Seminars in Cutaneous Medicine and Surgery ”
    Marc R. Avram
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    TLDR Hair transplantation has improved to more natural-looking results and is complemented by effective non-surgical treatments, with ongoing research into hair follicle cloning.
    In June 2002, the article reviewed the evolution of hair transplantation from the 1960s, highlighting the shift from large, unnatural-looking grafts to smaller 1-4 hair grafts that offer a more natural appearance. The author noted improvements in donor harvesting, graft size, hairline design, and the transition from steel punches to scalpels, which reduced scarring. The article also discussed the limited use of CO₂ lasers due to adverse effects, while the erbium laser was under investigation for its potential benefits. Medical therapies like minoxidil and finasteride were acknowledged as effective non-surgical treatments. The document emphasized the importance of realistic expectations, appropriate candidate selection, and the potential of future hair follicle cloning to address donor hair limitations.
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      community Boys I am just a gonner. What on earth is my scalp even going through. Looks like world war 3. Pyril 3 months. Topical melitonin/progesterone/fin, dut, fin, oral min, laser trash, anus stimulation. Nothing. Donor area is decimated 😂.

      in Progress Pictures  83 upvotes 2 years ago
      Treating Seborrheic Dermatitis, a fungal scalp condition which can cause hair loss. Treatments discussed include antifungal shampoos, cold showers, exfoliating the scalp, taking Vitamin D, and stimulating the prostate through the anus.

      community Verteporfin and Microneedling

      in Treatments 5 months ago
      Clinical studies by Dr. Barghouthi and Dr. Bloxham indicate that Verteporfin, when used with FUE and FUT hair transplantation methods, shows promise in hair follicle regeneration and minimal scarring due to its ability to inhibit Yes-associated protein (YAP). Microneedling at depths of 3-3.5mm, combined with Verteporfin, could potentially reactivate dormant follicles, although the optimal dosage and application method are still under investigation. Concerns remain about the DHT sensitivity of regenerated follicles, highlighting the need for further research to optimize trauma levels and Verteporfin concentrations to achieve effective and scar-free hair regeneration.
      Diffuse hair loss and scalp biopsies

      community Diffuse hair loss and scalp biopsies

      in Research  692 upvotes 3 months ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community Planning to for Hair transplant

      in Transplants  104 upvotes 8 months ago
      The conversation is about someone considering a hair transplant due to ineffective hair loss treatments, with suggestions ranging from trying a hairpiece to continuing with medications like finasteride and minoxidil, and waiting for new treatments. Some advise against a transplant due to the extent of hair loss and the cost, while others share different views on the effectiveness of transplants and non-surgical options.

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