research Skin Steroidogenesis in Health and Disease
The skin's ability to produce hormones is linked to various skin conditions, and better understanding this process could lead to new treatments.
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research Apoptosis May Explain the Pharmacological Mode of Action and Adverse Effects of Isotretinoin, Including Teratogenicity
Isotretinoin's effects and side effects, like birth defects and depression, might be due to it causing cell death in various cells.
research Insulin Sensitivity, Androgens, and Isotretinoin Therapy in Women with Severe Acne
Isotretinoin improves severe acne without changing androgen or insulin levels but may increase body weight and triglycerides.
research Recent Advances in the Molecular Mechanisms Determining Tissue Sensitivity to Glucocorticoids: Novel Mutations, Circadian Rhythm, and Ligand-Induced Repression of the Human Glucocorticoid Receptor
New findings explain how genetic changes, body clocks, and certain molecules affect tissue response to stress hormones.
research Retinoids and Phototherapy for Psoriasis
Retinoids and narrowband UVB phototherapy are effective for treating psoriasis and can reduce treatment time when used together.
research Predisposing and Overall Effects of Reproductive Hormones on Breast Cancer: A Review
Reproductive hormones play a crucial role in breast cancer development and treatment challenges.
research Cosmeceuticals
Isotretinoin and tazarotene help treat acne, while minoxidil and finasteride promote hair growth.
research Cloning of a Functional Vitamin D Receptor from the Lamprey, an Ancient Vertebrate Lacking a Calcified Skeleton and Teeth
Lampreys have a functional vitamin D receptor that may help detoxify harmful substances.
research Stem Cells and the Circadian Clock
The circadian clock influences the behavior and regeneration of stem cells in the body.
research Adverse Reactions to Oral Retinoids: An Update
Oral retinoids can cause side effects ranging from mild to severe, including birth defects, and require careful monitoring and contraception.
research Acneiform Dermatoses
Some skin conditions look like acne but are caused by drugs, and they usually get better when the drug is stopped.
research Neuroendocrinology of Epithelial Hair Follicle Stem Cells
Hormones and neuroendocrine factors control hair growth and color, and more research could lead to new hair treatment options.
research Interactions of the Vitamin D Receptor with the Corepressor Hairless
Most Hairless gene mutations reduce its ability to work with the Vitamin D Receptor, which might explain a certain type of hair loss.
research Evaluation of Clinical Adverse Effects and Laboratory Changes in Patients with Acne Vulgaris Treated with Oral Isotretinoin
Isotretinoin is safe and effective for acne, with common side effects like dry lips; serious side effects are rare.
research Dorsal Skin Reactions of Hairless Dogs to Topical Treatment with Corticosteroids
Stronger corticosteroids cause more skin damage in hairless dogs, similar to effects in humans.
research Single-Cell Transcriptomic Analysis of Small and Large Wounds Reveals the Distinct Spatial Organization of Regenerative Fibroblasts
Different types of skin cells are organized in a special way in large wounds to help with healing and hair growth.
research CAG Repeat Testing of Androgen Receptor Polymorphism: Is This Necessary for the Best Clinical Management of Hypogonadism?
Testing for CAG repeat polymorphism in the androgen receptor gene is not currently recommended for managing hypogonadism.
research The TFIID Subunit TAF4 Regulates Keratinocyte Proliferation and Has Cell-Autonomous and Non-Cell-Autonomous Tumor Suppressor Activity in Mouse Epidermis
TAF4 is important for skin cell growth and helps prevent skin cancer in mice.
research Thyroid Hormone Action on Skin
Thyroid hormones affect skin texture, hair and nail growth, and can cause skin diseases related to thyroid problems.
research Consensus on the Use of Oral Isotretinoin in Dermatology - Brazilian Society of Dermatology
The Brazilian Society of Dermatology agrees that oral isotretinoin is effective for acne and other skin conditions, and it's safe when monitored, but more research is needed on dosing and duration.
research Skin Diseases Due to Endocrine Alterations
Hormone imbalances can cause skin diseases, and understanding these links is important for diagnosis and treatment.
research Evaluation of Ovarian Reserve and Function in Female Patients Treated with Oral Isotretinoin for Severe Acne: An Exploratory Study
Oral isotretinoin for severe acne can change hormone levels but does not significantly affect ovarian function.
research Frontal Fibrosing Alopecia and Lichen Planopilaris in HLA-Identical Mother and Daughter
A mother and daughter with similar hair loss conditions and identical HLA types suggest a genetic link between the conditions.
research Effects of Isotretinoin on the Hair Cycle
Isotretinoin at a low dose for three months does not significantly affect hair growth.
research A 5α-Reductase Inhibitor, Finasteride, Increases Differentiation and Proliferation of Embryonal Carcinoma Cell-Derived Neural Cells
research The Role of Dietary Supplements in Hair Loss Treatment: A Review of Evidence
Some supplements may help with hair loss, but there's not enough strong evidence to recommend them without doctor advice.
research A Practitioner's Guide to Hair Loss: Part 2—Diet, Supplements, Vitamins, Minerals, Aromatherapy, and Psychosocial Aspects
Non-drug methods like diet, supplements, and aromatherapy can help manage hair loss and its emotional impact.
research Vitamins as Key Modulators in Hair Growth Dynamics
Vitamins A, B7, C, D, and E are essential for healthy hair growth and preventing damage.
research Transcriptomic Analysis to Identify Protective Dermal Papilla Signature in Occipital Scalp
The research found genes that may protect certain scalp cells from hair loss.
research Hair Follicle Culture
Hair follicle culture helps study hair growth but has limitations in modeling the full hair cycle.