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Retinoic acid production and signaling in hair follicles are regulated by location and timing, affecting hair growth and cycling.

Genetic variations affect dutasteride treatment response for male pattern hair loss.

Altered retinoid metabolism in cicatricial alopecia suggests a balanced vitamin A diet may prevent the condition.

Certain mouse strains develop a skin condition similar to a human hair loss disease due to genetic defects.

Eating too much or too little vitamin A can cause hair loss.

People with alopecia areata have higher levels of RBP4 protein and antibodies against it.

Two enzymes regulate androgen receptor activity, affecting treatments for androgen insufficiency and benign prostatic hyperplasia.

The enzyme RDH12 plays a role in vision and retinal disease, with mutations leading to early onset visual loss and blindness, but the exact disease mechanism is unclear and there are no treatments yet.

Vitamin A is important for healthy skin and hair, influencing hair growth and skin healing, but UV light reduces its levels.

The same genetic mutation in Sjögren-Larsson syndrome can lead to different levels of severity, suggesting other factors influence the symptoms.

Mice without certain skin enzymes have faster hair growth and bigger eye glands.

Retinoic acid affects male and female muscle energy use and function differently.

Estrogen affects how vitamin A is processed in mouse skin, which may impact acne treatment, hair growth, and skin defense.

Ozone therapy might improve cancer treatment and reduce its side effects.

Creating stronger blockers for skin enzymes might lead to better treatment for conditions like acne and excessive hair growth.

Eating more vitamin A changes hair growth-related proteins in mice, affecting hair cycle stages.

Antiandrogens and androgen inhibitors like spironolactone, finasteride, and dutasteride can treat hair loss and skin conditions, but they have risks and side effects, including potential harm to pregnant women and risks of cancer and heart issues. Herbal remedies also have antiandrogenic effects but lack safety validation.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

Hair can regrow in large wounds through a process similar to how hair forms in embryos, and understanding this could lead to new treatments for hair loss or scarring.

Understanding how DHT works is important for diagnosing and treating hormone-related disorders.

Targeting colon cancer stem cells might lead to better treatment results.

Isotretinoin may cause temporary, reversible facial hair growth in some women.

The review concludes that innovations in regenerative medicine, tissue engineering, and developmental biology are essential for effective tissue repair and organ transplants.

Finasteride in male rats causes liver and metabolic issues in their offspring.

The medication lopinavir-ritonavir may cause severe hair loss.

Hair loss can be caused by stress, infections, drugs, and various diseases, with treatment depending on accurate diagnosis.

The congress highlighted new gene therapy techniques and cell transplantation methods for treating diseases.

New partnerships, clinical trials, and drug approvals marked progress in therapeutic delivery in July 2018.

Enzymes are classified into six types and are essential for many biological processes, with only a few targeted by drugs.

Noncoding dsRNA boosts hair growth by activating TLR3 and increasing retinoic acid.