2 citations,
November 2017 in “Elsevier eBooks” Different substances that activate or block the androgen receptor can affect male development and treat conditions like prostate cancer.
Hair transplants are effective for male and female pattern baldness, have evolved in technique, and require careful planning for natural results and managing complications.
1 citations,
January 2018 in “Springer eBooks” The document concludes that scalp cooling and treatments like minoxidil can help manage hair loss from cancer therapy.
October 2024 in “International Journal of Pharmaceutical Sciences Review and Research” This study explores a film-forming spray with 5% minoxidil for treating androgenetic alopecia, aiming to reduce side effects like dry scalp and irritation associated with traditional formulations. The spray forms a thin, non-sticky film that enhances drug contact time and permeability, leading to continuous release and improved patient comfort. The formulation was evaluated for pH, viscosity, spray angle, and drug content, with formulation F2 (1.8% hydroxypropyl methylcellulose E15) showing promising results. The study concludes that this novel delivery system could effectively treat patchy hair loss or baldness in men with androgenetic alopecia, improving therapeutic outcomes and patient compliance.
January 2018 in “Elsevier eBooks” Minoxidil helps lower severe blood pressure and promotes hair growth but can have serious side effects and must be used continuously.
December 2014 in “Bali Medical Journal” Females have higher estrogen receptor levels in hair than males, and these levels decrease in white hair compared to black hair.
January 2012 in “Human health handbooks” Low-level light therapy is FDA-approved for male pattern hair loss, increases hair count and strength, and is considered safe for use.
417 citations,
September 2005 in “PLoS biology” Understanding gene expression in hair follicles can reveal insights into hair growth and disorders.
205 citations,
March 2012 in “Science Translational Medicine” PGD2 stops hair growth and is higher in bald men with AGA.
187 citations,
December 2005 in “Experimental Dermatology” Estrogens can improve skin aging but carry risks; more research is needed on safer treatments.
163 citations,
November 2003 in “Journal of Investigative Dermatology” Low iron levels may be linked to some types of hair loss in women.
140 citations,
April 2004 in “The journal of investigative dermatology/Journal of investigative dermatology” The enzyme 25 Hydroxyvitamin D 1 α-Hydroxylase is essential for healthy skin and recovery after skin damage.
103 citations,
November 2014 in “Journal of Cell Biology” MicroRNA-214 is important for skin and hair growth because it affects the Wnt pathway.
87 citations,
January 2016 in “Development” Blocking β-catenin in skin cells improves hair growth during wound healing.
86 citations,
July 2020 in “International Journal of Molecular Sciences” Activating the Wnt/β-catenin pathway could lead to new hair loss treatments.
86 citations,
July 1990 in “British Journal of Pharmacology” Diazoxide, minoxidil sulphate, and cromakalim relax rat blood vessels by opening K+ channels, with some differences in their actions.
81 citations,
June 2014 in “American Journal of Men's Health” Finasteride can cause lasting sexual, emotional, and cognitive issues, with varying severity.
81 citations,
February 1997 in “Journal of Investigative Dermatology” Minoxidil boosts hair growth by activating PGHS-1.
78 citations,
March 1987 in “Journal of The American Academy of Dermatology” Minoxidil promotes hair growth but stops working when discontinued.
70 citations,
February 2017 in “Dermatologic Surgery” Treatment with plasma rich in growth factors improved hair density and thickness for hair loss patients.
67 citations,
January 2007 in “Climacteric” Estrogens and SERMs can help with skin aging, but their safety and effectiveness need more research.
54 citations,
June 1985 in “American Journal of Dermatopathology” Minoxidil helps grow longer, thicker hair in bald scalps of stumptailed macaques, and early treatment is more effective.
47 citations,
January 2019 in “Nature communications” Polyamines help fix DNA damage accurately in cells.
41 citations,
July 2015 in “Current Drug Discovery Technologies” Some plants may help with hair growth and have fewer side effects than synthetic drugs, but more research is needed to confirm their effectiveness.
34 citations,
April 2009 in “Expert Opinion on Pharmacotherapy” Some treatments work for common baldness, but there's less evidence for other hair loss types, and more research is needed.
33 citations,
February 1999 in “The journal of investigative dermatology/Journal of investigative dermatology” IGF-1 increases whisker growth in transgenic mice.
31 citations,
March 2013 in “Gene” Signaling pathways are crucial for hair growth in goats.
31 citations,
April 1999 in “Dermatologic Clinics” Nd:YAG laser can reduce hair with multiple treatments, but permanent removal isn't guaranteed.
30 citations,
November 2018 in “EMBO Reports” The Ovol2-Zeb1 circuit is crucial for skin healing and hair growth by guiding cell movement and growth.
30 citations,
January 2000 in “Dermatologic Clinics” Finasteride and minoxidil are effective FDA-approved treatments for androgenetic alopecia.