35 citations
,
December 2017 in “Journal of Experimental Botany” In this study, CSLD3 overexpression in Arabidopsis enhanced root and hypocotyl growth by increasing cell elongation, with root growth highly sensitive to ethylene and phosphate starvation conditions.
30 citations
,
October 2012 in “Developmental Biology” 30 citations
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January 2001 in “Journal of the American Veterinary Medical Association” This study found that adrenal sex hormone levels were elevated in neutered dogs with hypercortisolemia, except for testosterone, highlighting the importance of ruling out hypercortisolemia when diagnosing adrenal hyperplasia syndrome.
30 citations
,
January 1999 in “Dermatology” This study found that cyclosporine A may lead to partial hair regrowth in 50% of patients with severe alopecia areata who do not respond to standard treatments.
26 citations
,
April 2024 in “Particle and Fibre Toxicology” In this study, researchers investigated the penetration and cellular responses to nanoplastics in human skin models with compromised barriers, finding that nanoplastics can penetrate the skin, accumulate in cells, and trigger inflammatory responses through specific signaling pathways.
24 citations
,
March 1987 in “Journal of The American Academy of Dermatology” This study found that 1% and 2% topical minoxidil solutions resulted in clinically noticeable hair growth compared to lower doses or placebo in men with male pattern baldness.
22 citations
,
June 2012 in “PLOS ONE” In this study, researchers found that impaired cholesterol biosynthesis in hair follicles may trigger an inflammatory immune response linked to primary cicatricial alopecia, providing new insights into the disorder's pathogenesis.
22 citations
,
December 1992 in “The journal of pediatrics/The Journal of pediatrics” This study reported that oral zinc therapy improved hair and skin abnormalities in patients with dry brittle hair, alopecia, and other symptoms, regardless of demonstrated zinc deficiency.
20 citations
,
July 2017 in “Journal of Investigative Dermatology” IL-1 receptor absence in mice leads to skin cysts and changes in immune response after UVB exposure.
19 citations
,
May 2009 in “Pediatric Dermatology” This case report describes a 5-year-old girl with childhood discoid lupus erythematosus, where treatment led to reversal of scarring alopecia and hair regrowth.
18 citations
,
November 2007 in “Annals of Surgery” Finasteride reduces inflammation and improves immune response after trauma by altering hormone levels.
15 citations
,
April 2022 in “Immunology” This review discusses sex differences in immune responses to COVID-19 and highlights that males tend to experience more severe symptoms and higher mortality but reports no new clinical findings.
15 citations
,
March 2018 in “Journal of The American Academy of Dermatology” This study found that platelet-rich plasma combined with other hair restoration therapies significantly increased hair density in patients with androgenetic alopecia, though it did not statistically affect hair shaft diameter.
11 citations
,
May 2019 in “Journal of Cosmetic Dermatology” This case report observed significant improvement in hair density and thickness in a male patient with androgenetic alopecia following the addition of mesotherapy, alongside topical minoxidil and oral finasteride, over 20 sessions, with no side effects reported.
11 citations
,
August 2016 in “Journal of the European Academy of Dermatology and Venereology” This letter discusses the use of serial trichoscopy versus a modified hair pull test for monitoring localized alopecia areata but reports no new clinical results.
This study found that hair follicles across mouse skin form a heterogeneous regenerative field, with distinct cycling dynamics influenced by the balance of activator and inhibitor signals, which could inform other organ regeneration research.
3 citations
,
January 2016 In this study, NuMA's microtubule-binding domain was found to be crucial for correct spindle orientation and skin differentiation, with its loss leading to neonatal lethality in mice.
This study discovered that the transcription factor FoxA is crucial for the regeneration of the planarian pharynx, revealing its new role in organ-specific regeneration.
2 citations
,
May 2024 in “Immunity” In this study, Luan et al. showed that epidermal stem cells play a key role in wound healing by coordinating the recruitment of regulatory T cells and neutrophils, which help balance immune tolerance and inflammation.
2 citations
,
January 2022 in “Skin appendage disorders” This study presents two cases where intralesional methotrexate combined with ablative fractional CO2 laser treatment resulted in excellent outcomes for refractory alopecia areata.
2 citations
,
October 2020 in “Journal of The American Academy of Dermatology” This research discusses androgenic alopecia's potential role in severe COVID-19 symptomatology and suggests further exploration of the scalp's role in virus transmission.
2 citations
,
September 2020 This Mendelian randomization study reports that lifelong increased free testosterone in males was associated with improved bone mineral density and body composition but increased risks of prostate cancer, hypertension, and several other conditions.
2 citations
,
March 2019 in “Lasers in surgery and medicine” This study found that human hair follicles demonstrated a dose-dependent response to light in an ex vivo photoepilation model, which could predict the clinical efficacy and permanency of light-based hair removal devices.
1 citations
,
August 2021 in “Journal of The American Academy of Dermatology” This study evaluates the effectiveness and safety of 2-mg and 4-mg doses of baricitinib in patients with alopecia areata who have lost at least 50% of their scalp hair, comparing outcomes between those with early and late onset of the disease.
1 citations
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May 2021 in “International Journal Of Medical Science And Clinical Invention” This review discusses the potential risk mechanisms for COVID-19 in women with polycystic ovarian syndrome due to hyperandrogenism and calls for further research, but reports no new findings.
This study found that some white or grey human hairs can naturally regain pigmentation, suggesting a potential temporary reversibility of hair greying associated with stress and molecular changes.
1 citations
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April 2021 in “Journal of the American Academy of Dermatology” This retrospective review found that platelet-rich plasma products from FDA-cleared devices for alopecia were inconsistent, highlighting a need for more detailed examination of preparation methods.
1 citations
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October 2020 in “Journal of Investigative Dermatology Symposium Proceedings” This study found that platelet-rich plasma treatment increased hair density and reduced inflammation in patients with patchy alopecia areata, but not in a patient with alopecia universalis.
This study found that a combination of four transcription factors can transform mouse fibroblasts into cells resembling inner ear hair cells, potentially aiding research into hearing loss treatments.
1 citations
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October 2019 This study found that skin-infiltrating neutrophils play a crucial role in triggering chronic itch in atopic dermatitis by promoting skin hyperinnervation and enhanced expression of itch signaling molecules in a mouse model.