Successful Response to a Combination of Intralesional Methotrexate and Fractional CO2 Laser in Refractory Alopecia Areata: Case Report

The user has been using minoxidil irregularly and recently added KX826 to their regimen, considering switching to oral minoxidil due to hair loss and thyroid issues. They are hesitant about finasteride due to potential side effects but are exploring other anti-DHT solutions.

Finasteride and dutasteride are discussed for hair loss, with concerns about their effects on neurosteroids and potential side effects like depression. Alternatives like topical estrogen and lifestyle changes are considered, with varying opinions on mental health and hair regrowth.

The user is disappointed with the lack of visible progress in hair regrowth after 6 months of using finasteride and minoxidil. Another user suggests adding a topical anti-androgen like kx826, while encouraging patience as changes may start to show between 6-9 months.

The user experienced significant hair regrowth using 1+ mg of finasteride and 2.5 mg of minoxidil, later increasing to 5 mg, along with dermarolling. They reported no negative side effects and noted improved libido.

Stopping Dutasteride may temporarily affect sperm quality, but it typically returns to normal within a few months. Minoxidil and Dutasteride are used for hair maintenance, and Mucuna Pruriens and hCG are suggested for improving sperm quality.

The user experienced hair regrowth and stopped hair loss after taking finasteride three times a week without side effects. Discussion included the importance of scalp sensitivity to DHT and the use of topical dutasteride.