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PCOS is a long-term condition that needs more research for better understanding and treatment.

Testosterone changes important cell communication proteins in pregnant rats' uteruses, which might affect pregnancy success.

The right dosage of CPA and TB can work as a safe and reversible male contraceptive in monkeys.

Testosterone therapy can improve sexual function in women but long-term safety is unclear.

Sunekos® effectively improves labia majora appearance and is well-tolerated.

Skin problems like excessive hair growth, acne, and dark skin patches can be signs of Polycystic Ovarian Disease, which may also be linked to family history and a risk for diabetes.

Some patients may experience lasting sexual dysfunction, depression, and other side effects from 5α-reductase inhibitor therapy.

Larger prostate size in older men may be linked to poorer semen quality and fertility issues.

The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.

Some patients taking finasteride or dutasteride may have ongoing sexual problems and depression even after stopping the medication.

The guidelines suggest a detailed approach to diagnosing and treating lupus, with a focus on regular check-ups, personalized medicine, and a range of drug options for different cases.

Diagnosing PCOS in teenagers is challenging and should use strict criteria to avoid misdiagnosis and unnecessary worry.

Lifestyle changes can improve body composition, excess male hormone levels, and insulin resistance in women with PCOS.

Male and female bodies respond differently to stress, influenced by hormones and development stages, with implications for stress-related diseases.

Melatonin may benefit skin health and could be a promising treatment in dermatology.

Cyproterone acetate-estrogen most effective for hirsutism, but consider side effects and patient needs.

South Asian women with PCOS are more likely to have metabolic issues and central obesity, and simple measures like waist size and blood pressure can help identify these risks early.

Women with androgenic alopecia are more likely to have polycystic ovaries and higher androgen levels, which may indicate PCOS.

Women with PCOS who have low SHBG are more likely to have low good cholesterol and metabolic syndrome.

Women with PCOS have fewer activated T cells in their ovarian follicles, which might affect fertility.

The review recommends hormone replacement therapy for women with premature ovarian insufficiency to manage symptoms and protect health, with specific approaches for different groups.

Dihydrotestosterone increases the activity of an enzyme in pubic skin cells that converts testosterone to dihydrotestosterone.

Eating healthy, exercising, and taking certain supplements can help manage Polycystic Ovary Syndrome symptoms.

Dietary changes, including weight loss and a balanced diet, are important for managing PCOS, especially in overweight women.

Testosterone therapy can help improve sexual desire and function in postmenopausal women but may cause side effects and is not FDA-approved for this use.

Ketoconazole reduced hair growth and improved acne in women, but caused side effects needing careful monitoring.

Some women with PCOS have CYP21 mutations and IRS1 variants, but these genetic factors are not major contributors to PCOS.

5-alpha reductase deficiency leads to male sexual development issues and treatments like finasteride help with prostate enlargement and hair loss.

Women with PCOS tend to have higher anxiety and depression levels compared to healthy women.

Menstrual disorders are common in adolescents and can be influenced by weight, activity, and health issues, requiring careful evaluation and more research for effective treatment.