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Mutations in the androgen receptor gene cause different levels of androgen insensitivity, making it hard to create simple tests for the condition.

Mice without the vitamin D receptor have bone issues and other health problems, suggesting vitamin D is important for preventing various diseases in humans.

Male hormones may play a role in the development of heart disease, and more research is needed to understand their effects.

VEGF helps hair grow and determines follicle size by increasing blood vessel growth.

Anabolic steroids can build muscle and strength but have risks and need more research on their clinical benefits and side effects.

Experts recommend using evidence-based methods to diagnose and treat hirsutism, focusing on symptoms and underlying causes.

Human skin makes sexual hormones that affect hair growth, skin health, and healing; too much can cause acne and hair loss, while treatments can manage these conditions.

The document likely offers guidance on treating a woman's excessive hair growth, considering her symptoms and obesity.

Exposure to too much androgen before birth might cause polycystic ovary syndrome later in life.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

High levels of male hormones, insulin resistance, and obesity are closely linked and worsen polycystic ovary syndrome, but more research is needed to improve treatments.

Dutasteride and finasteride may reduce sperm count and volume but don't affect movement or shape; effects are reversible after stopping.

Metformin is effective for treating excessive hair growth in women with PCOS and may work better than the standard treatment in some ways.

Estrogens can improve skin aging but carry risks; more research is needed on safer treatments.

Finasteride treats enlarged prostate and may help with baldness, but effects on sexual function and male fetuses are unclear.

Melatonin may benefit skin health and could be a promising treatment in dermatology.

Pectin biosynthesis is essential for the growth of cotton fibers and Arabidopsis root hairs.

Stress-related substance P may lead to hair loss and negatively affect hair growth.

Tributyltin exposure causes sex changes, sterilization, and decline in the snail Ocinebrina aciculata, risking its extinction.

The enzyme 25 Hydroxyvitamin D 1 α-Hydroxylase is essential for healthy skin and recovery after skin damage.

Estrogen replacement can improve skin health in menopausal women but doesn't reverse sun damage or prevent hair loss.

Modulating BMP activity changes the number, size, shape, and type of ectodermal organs.

Finasteride exposure in pregnancy causes genital abnormalities in male rats.

Androgens have complex effects on hair growth, promoting it in some areas but causing hair loss in others, and our understanding of this is still evolving.

People with PCOS, especially if obese, often have NAFLD, linked to obesity, insulin resistance, and high androgen levels.

Men, especially older ones with health issues like prostate cancer, may have worse COVID-19 outcomes and could benefit from therapies targeting male hormones.

Too much Smad7 can cause serious changes in skin tissues, including problems with hair growth, thymus shrinkage, and eye development issues.

More men are getting benign prostatic hyperplasia, and there are many treatments, from medication to surgery, with new methods being developed.

Testosterone replacement may help some postmenopausal women with symptoms like fatigue and low libido, but more research is needed to fully understand its effects.

A new gene mutation causes female pseudohermaphroditism due to glucocorticoid resistance.