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This study found that dual inhibition of BACE1 and BACE2 in mice affects melanosome maturation and causes dose-dependent hair depigmentation without altering retinal morphology.

This case report describes an elderly multiple myeloma patient whose hair repigmentation was associated with lenalidomide use, suggesting hair graying may be reversible.

White hair patch repigmented and hair regrew in a balding patient after treatment with exosomes and laser.

This study analyzed gray hair, revealing that it differs from pigmented hair in follicular activity, oxidative balance, and structure, impacting coloring processes and necessitating adapted techniques to maintain hair quality.

This study found that the expression of CK 15 and CK 19 in vitiligo patients undergoing phototherapy was correlated with improved repigmentation, suggesting their potential as markers for stem cell stimulation.

This article reviews the process of repigmentation in vitiligo and emphasizes the role of UV light as the most potent stimulus, with no new clinical findings reported.

This narrative review proposes the concept of "repigmentation competence" for vitiligo lesions, suggesting that therapy responses are influenced by lesion-specific biological factors related to immune, regenerative, regulatory, and microenvironmental processes, and highlights the emerging role of combination therapies targeting these pathways.

This review discusses various techniques for depigmentation in vitiligo patients and suggests that cryotherapy, performed by an experienced professional, may be the most cost-effective and accessible method.

Understanding repigmentation mechanisms in vitiligo can improve treatments and patient outcomes.

This letter reports repigmentation of hair in patients receiving latanoprost therapy.

In this study, researchers found that Langerhans' cells likely do not play a role in the depigmentation process in C57Bl/Ler-vit.vit mice, as their number was normal during depigmentation and highest afterward.

A new gene mutation may allow some piebaldism patients to regain skin color in white patches.

This review examines the differential aging of melanocytes in hair follicles and skin, and reports no new findings; the authors suggest further research is needed to understand these processes.

In this study on a mouse model of vitiligo, NB-UVB/ADSC combination therapy improved oxidative stress and calcium homeostasis, but the protective effect was reversed by inhibiting Nr2 signaling.

Cyclosporine can reverse hair graying.

This article discusses localized repigmentation of hair, suggesting it may be an indicator of underlying melanoma, and emphasizes the need for careful diagnostic evaluation.

This study documented that after hair transplantation, 34 patients with white or gray hair in the donor area experienced color repigmentation, with most regaining their original blackish color in the recipient area over a 1-year follow-up.

This study concluded that controlled micro-injury induces hair regeneration and vitiligo repigmentation in mice, potentially through the Wnt/β-catenin pathway.

This review discusses the changes in hair follicles with aging, particularly graying due to decreased melanocyte activity, and suggests potential for hair repigmentation under certain conditions, but reports no new results.

In this study, researchers concluded that Langerhans' cells are likely uninvolved in depigmentation during vitiligo in C57Bl/Ler-vit vit mice, as their numbers were normal during depigmentation and increased afterward.

This study found that pimecrolimus enhances melanin synthesis and promotes melanocyte migration, possibly by increasing MITF protein expression, which may explain its effectiveness in repigmenting vitiligo.

This study found that certain proteins linked to immune suppression and melanogenesis are associated with repigmentation in vitiligo patients undergoing standard treatment, suggesting these proteins and their pathways play roles distinct from merely reversing skin lesions.

This chapter reviews surgical management techniques for leukotrichia in vitiligo and presents no new clinical findings; it highlights various grafting and epilation methods.

The document suggests a bacteria plays a significant role in acne rosacea and that white hair can regain color after transplant, meriting more research on reversing grey hair.

This study explored the potential of silk fibroin methacrylate hydrogel microneedles to deliver α-MSH directly to the epidermis in vitiligo patients, enhancing melanocyte protection and melanosome transfer, potentially offering a new treatment avenue for this challenging condition.

This study found that puerarin, derived from Pueraria thunbergiana, may stimulate melanogenesis and prevent follicular depigmentation in a hair graying mouse model.

This article reviews drug-induced hair and nail disorders and discusses their clinical recognition, underlying mechanisms, and potential treatment strategies, without presenting new research findings.

This review summarizes the potential therapeutic applications of stem cells in dermatology, emphasizing their role in restorative and regenerative treatments through injections, topical applications, and scaffolds, supported by advancements in laboratory processes and quality control.

COVID-19 might cause gray hair to regain color.

This review discusses surgical treatments for vitiligo, emphasizing the importance of proper preparation of the recipient site to improve cosmetic outcomes, while highlighting ongoing research and trials.