Hair Repigmentation of Poliosis Circumscripta in Androgenetic Alopecia Patient Treated With Exosomes and Fractional Picosecond Laser

A 38-year-old male with androgenetic alopecia (AGA) and poliosis circumscripta, a localized patch of white hair, was treated with exosomes and fractional picosecond laser (FPL) treatment. The patient showed clinical improvement in hair regrowth and repigmentation of the white hair patch after four sessions of treatments. Exosomes, which play a central role in hair morphogenesis and regeneration, have anti-inflammatory effects, antioxidative stress properties, regulate pigmentation processes, and promote the hair growth cycle. However, the study's limitations include its basis on a single case report and the concurrent use of FPL therapy, limiting the generalizability of the results. More extensive, controlled research is needed for definitive conclusions.