Successful Treatment of Hair Loss and Restoration of Natural Hair Color in Patient with Alopecia Areata Due to Psychological Disorder Using Exosomes: Case Report with 6-Month Follow-Up

    May 2025 in “ Cosmetics ”
    Emanuel Barbosa Bento, Christiano J. S. de Matos, Howard Lopes Ribeiro
    Studysummary This case study highlights rose stem cell-derived exosomes combined with thulium laser therapy as a promising treatment for stress-induced alopecia areata, achieving significant hair regrowth and pigmentation without corticosteroid side effects, though further research is needed for broader application.
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    Research cited in this study 15

    1. The Efficacy of Adipose Stem Cell-Derived Exosomes in Hair Regeneration Based on a Preclinical and Clinical Study International Journal of Dermatology · 2024
    2. Rose Stem Cell-Derived Exosomes for Hair Regeneration Enhancement via Noninvasive Electroporation in Androgenetic Alopecia Journal of Cosmetic Dermatology · 2024
    3. Hair Repigmentation of Poliosis Circumscripta in Androgenetic Alopecia Patient Treated With Exosomes and Fractional Picosecond Laser Journal of Cosmetic Dermatology · 2024
    4. European Expert Consensus Statement on the Systemic Treatment of Alopecia Areata JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology · 2024
    5. Use of Fractionated Laser Therapy for the Treatment of Androgenetic Alopecia: A Systematic Review and Meta-Analysis Lasers in Medical Science · 2023
    6. Exosomes Derived From Umbilical Cord Mesenchymal Stem Cells Promote Hair Regrowth in Alopecia Areata Cell Biology International · 2023
    7. Alopecia Areata: What's New in the Epidemiology, Comorbidities, and Pathogenesis? Journal of Dermatological Science · 2023
    8. Alopecia Areata: Current Treatments and New Directions American Journal of Clinical Dermatology · 2023
    9. Psychological Stress-Induced Pathogenesis of Alopecia Areata: Autoimmune and Apoptotic Pathways International journal of molecular sciences · 2023
    10. Treatment of Persistent Chemotherapy-Induced Hair Loss (Alopecia) With Human Mesenchymal Stromal Cells Exosome Enriched Extracellular Vesicles: A Case Report Heliyon · 2023
    11. The Association of Alopecia Areata-Related Emotional Symptoms with Work Productivity and Daily Activity Among Patients with Alopecia Areata Dermatology and Therapy · 2022
    12. Alopecia Areata: Current Understanding and Management Journal der Deutschen Dermatologischen Gesellschaft · 2022
    13. Psychological Aspects of Hair Disorders: Considerations for Dermatologists, Cosmetologists, Aesthetic, and Plastic Surgeons Skin appendage disorders · 2021
    14. Alopecia Areata: A Multifactorial Autoimmune Condition Journal of autoimmunity · 2018
    15. Therapeutic Efficacy and Safety of a 1927-nm Fractionated Thulium Laser on Pattern Hair Loss: An Evaluator-Blinded, Split-Scalp Study Lasers in Medical Science · 2018

    Related research 4

    1. Individualized Homeopathic Approach in Alopecia Areata: An Evidence-Based Case Report International Journal of Homoeopathic Sciences · 2023
    2. Alopecia Areata: A Multifactorial Autoimmune Condition Journal of autoimmunity · 2018
    3. Treating Resistant Cases of Alopecia Universalis Journal of cosmetology & trichology · 2018
    4. Management of Autoimmune-Associated Alopecia Areata Nursing Standard · 2010