June 2019 in “PRISM (University of Calgary)” This research reported that dermal progenitor cells can enhance split-thickness skin graft outcomes by improving dermal layer qualities and reducing itch and offer potential in skin wound healing using a flowable hydrogel for better cell delivery and survival.
December 2024 in “Microorganisms” This study analyzed changes in the microbiota during antler velvet regeneration in sika deer and found significant differences in microbial community composition between 15 and 30 days post-pedicle casting, highlighting the potential roles of specific bacteria in wound healing and tissue regeneration.
7 citations
,
January 2013 in “BioMed research international” This review highlights surprising similarities between hair follicles and antler units, suggesting that a comparative study of their biology could benefit understanding in both areas without presenting new empirical findings.
9 citations
,
November 2018 in “Drug Discovery Today” This review discusses insights from scar-free animal models and cellular factors in skin regeneration, suggesting potential strategies for developing scar-free treatments in clinical and cosmetic practices, but reports no new clinical results.
This study found that late embryonic skin injuries can regenerate multiple tissue types, but this ability is hindered postnatally due to fibroblast-driven hyperinnervation, which can be mitigated to enable regeneration.
23 citations
,
January 2019 in “Journal of wildlife diseases” This study found that a significant number of boreal woodland caribou in NE British Columbia showed symptoms of trace mineral deficiencies and exposure to various pathogens, with substantial winter tick infestations affecting a majority of individuals.
21 citations
,
August 2024 in “Journal of Animal Science and Biotechnology/Journal of animal science and biotechnology” This paper reviews the advancements and applications of single-cell transcriptomics in animal research, highlighting its potential to enhance understanding of animal nutrition, health, genetics, and disease models.
February 2026 in “Exploration” This review summarizes research on scar formation and inhibition mechanisms, discussing emerging therapies like gene therapy and stem cell treatments, but notes ongoing challenges for clinical application, including treatment personalization and outcome sustainability.
January 2013 in “Journal of Siberian Medical Sciences” This study found that patients with androgenetic alopecia experienced higher treatment efficacy when using a combination of antler-based products "Pantogematogen" and "Chudopan" compared to other methods.
90 citations
,
October 1998 in “Animal Reproduction Science” This study found that in captive mouflon rams, reproductive and physical maturation, marked by changes in hormone levels and physical attributes, progresses gradually across their life span, with sexual maturity tied closely to physical maturity.
12 citations
,
January 1981 in “Springer eBooks” Environmental factors like temperature and nutrition affect hair growth, with humans showing seasonal hair growth differences.
2 citations
,
November 2022 in “Veterinary sciences” This study found that the interdigital gland of Vembur sheep has larger secretory lobules in males than females, producing various compounds for chemical communication and foot protection.
25 citations
,
September 2014 in “SpringerPlus” This study found that sheep possess a polymorphic KAP8-2 gene that shares high sequence identity with the KAP8-2 gene in goats and reindeer.
6 citations
,
January 2016 in “Environmental footprints and eco-design of products and processes” This review discusses the use and sustainability challenges of luxury animal hair fibers in the fashion industry and reports no new research findings.
4 citations
,
April 2012 in “Asian-australasian Journal of Animal Sciences” This study found that applying deer antler extract to rat skin wounds enhanced hair growth and increased IGF-I expression, suggesting potential use in hair growth products.
4 citations
,
January 2014 in “The Scientific World Journal” This study found that deer antler aqueous extract may promote hair growth in mice by extending the anagen phase and increasing cell proliferation in the hair follicle region.
14 citations
,
February 2021 in “International Journal of Pharmaceutics” In this study, applying deer antler velvet extract-loaded niosomes and microspicules serum to the scalp significantly improved hair growth, melanin content, and skin hydration over 14 to 30 days without causing skin irritation.
18 citations
,
November 2010 in “Journal of morphology” This research examined the ultrastructure of deer hair fibers and found significant variations in diameter, cuticle thickness, and intermediate filament arrangements among different fiber types.
92 citations
,
March 2010 in “Gerontology” This review discusses the regenerative processes of deer antlers compared to other vertebrates and reports no new experimental findings, suggesting insights for regenerative medicine and cancer biology.
January 2008 in “Asian-Australasian Journal of Animal Sciences” In this study, red deer antler extract was found to promote hair growth and increase IGF-I expression in a rat wound healing model.
January 2023 in “Acta historiae medicinae stomatologiae pharmaciae medicinae veterinariae” This article reviews historical uses of male red deer parts in traditional medicine but provides no new research findings; it emphasizes their long-standing role in treatments for various health issues.
9 citations
,
January 2018 in “Stem Cells International” The researchers reported that conditioned media from deer antler mesenchymal stem cells may enhance hair and skin regeneration by modulating cellular responses through secretory vesicles.
15 citations
,
July 2004 in “Journal of Wildlife Diseases” In this study, ivermectin treatment in affected Columbian black-tailed deer was associated with increased weight gain, reduced parasites, and faster hair regrowth compared to untreated deer.
1 citations
,
May 2012 in “International Conference on Biomedical Engineering and Biotechnology” This study suggests that TGF-β receptor 1 may play a role in deer antler skin cell differentiation and dermis fibroblasts' rapid proliferation, potentially aiding the alignment of skin and cartilage growth rates in sika deer antlers.
15 citations
,
January 2016 in “Biological & Pharmaceutical Bulletin” This study found that bee venom promoted hair growth in mice and inhibited a key enzyme involved in testosterone conversion, suggesting its potential as a 5α-reductase inhibitor and hair growth promoter.
16 citations
,
August 1996 in “The journal of experimental zoology/Journal of experimental zoology” This study suggests that red deer stags provide a novel model for investigating hormonal regulation of hair growth due to the different cell growth rates in hair follicles during breeding and nonbreeding seasons.
24 citations
,
March 2001 in “Journal of Endocrinology/Journal of endocrinology” In this study, androgen receptors were found only in the mane follicles of red deer stags during the breeding season, suggesting their expression is induced by seasonal hormone changes.
7 citations
,
March 2021 in “Evidence-based Complementary and Alternative Medicine” This study found that Nelumbinis Semen extract may promote hair growth and reduce hair loss by increasing VEGF and IGF-1 expression and decreasing TGF-β1 in human dermal papilla cells and mice.
September 2025 in “JUKEJ Jurnal Kesehatan Jompa” This study found that 20% mung bean seed coat extract effectively stimulates hair growth in New Zealand White rabbits, demonstrating results close to minoxidil 2% in terms of hair length, weight, and growth area, suggesting its potential as a natural alternative for hair loss therapy.
2 citations
,
October 1999 in “Annals of the New York Academy of Sciences” This article discusses plasma β-endorphin concentrations during natural and artificially induced winter hair growth in mink but reports no new clinical findings.