May 2024 in “Tạp chí Y Dược học Cần Thơ” This research explored hair loss and regrowth, highlighting the use of animal models like mice and rats to better understand hair physiology, shedding cycles, and potential treatments, with implications for human application.
August 2016 in “Journal of Investigative Dermatology” In this animal study, zinc deficiency in mice was linked to disrupted hair cycles and impaired hair regrowth, which were reversed by zinc supplementation.
520 citations
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February 2001 in “Journal of Clinical Investigation” This study found that VEGF significantly enhances perifollicular vascularization during the hair growth phase, accelerating hair regrowth and increasing follicle and hair size, while its inhibition retards hair growth.
149 citations
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July 2014 in “Cold Spring Harbor Perspectives in Medicine” This article provides contact information for Bruce A. Morgan and features no new research findings.
42 citations
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June 2019 in “Aging” This study found that treatment with the polyphenolic compound TCQA activated β-catenin, promoting hair regrowth and the initiation of the anagen phase in mice and human dermal papilla cells.
32 citations
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May 2015 in “Journal of Investigative Dermatology” This study found that collagen VI influences hair follicle growth and wound-induced regrowth by activating the Wnt/β-catenin signaling pathway in mice, suggesting potential therapeutic targets for hair loss.
21 citations
,
January 2018 in “The Korean Journal of Physiology and Pharmacology” This study found that human umbilical cord blood mesenchymal stem cells promoted hair growth by advancing anagen onset and increasing hair follicle regeneration in an in vivo model.
19 citations
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December 2018 in “Experimental and Molecular Medicine” This study reports that the novel small molecule IM176OUT05, by modifying stem cell metabolism, promoted hair regrowth and increased hair follicle numbers in mice.
13 citations
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August 2016 in “Medical Hypotheses” This review discusses the potential of evaluating hair follicle characteristics as early indicators of vascular impairment and organ damage in pre-diabetic individuals, but reports no new clinical results.
13 citations
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February 2015 in “Actas Dermo-Sifiliográficas” This review discusses the histologic features of nonscarring alopecia and highlights the importance of clinical-pathological correlation for accurate diagnosis, but reports no new clinical results.
10 citations
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January 2013 in “Journal of The European Academy of Dermatology and Venereology” In this study, a square pulse, low-fluence IPL device used at home significantly reduced terminal hair count by 87% six months post-treatment, with evidence of hair miniaturization similar to professional laser treatments.
8 citations
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September 2017 in “Journal of Investigative Dermatology” This study found that inhibiting the interaction between CXXC5 and Dishevelled could stimulate hair regrowth in mouse models by enhancing WNT/β-catenin signaling, suggesting a potential therapeutic strategy for hair loss involving compounds that block this interaction, such as interfering short peptides.
5 citations
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November 2008 in “Advances in Dermatology” This review discusses advancements in understanding hair cycle and inflammatory alopecias, proposing a standard classification and tiered treatment recommendations, but reports no clinical results.
4 citations
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July 2014 in “Journal of Investigative Dermatology” This study suggests that age-related regenerative decline in hair follicles may be due to an imbalance of signals affecting stem cell activation, with follistatin potentially promoting renewal.
3 citations
,
October 2023 in “Military Medical Research/Military medical research” This review explores the crucial role of regulatory T cells in skin wound healing, emphasizing their involvement in balancing immune responses and promoting regeneration. It also discusses Tregs' operations in fibrosis, keloidosis, and scarring, suggesting a potential avenue for novel treatments.
3 citations
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May 2008 in “Hair transplant forum international” This document includes a brief professional profile of Dr. Ralf Paus but presents no research findings or study results.
1 citations
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May 2004 in “Journal der Deutschen Dermatologischen Gesellschaft” This article from the 4th Intercontinental Meeting of Hair Research Societies provides no abstract or new findings.
June 2026 in “Revista Brasileira de Saúde” This study reviewed current scientific evidence on the use of exosomes for treating alopecias, finding they may stimulate dermal papilla cell proliferation and modulate inflammation, though challenges in standardization and long-term efficacy remain.
June 2026 in “Journal of Cosmetic Dermatology” This study reported that microneedle-assisted delivery of PEGylated recombinant human fusion collagen significantly improved hair regrowth and density in an androgenetic alopecia mouse model and in a small clinical trial with AGA patients, suggesting potential efficacy and safety for this treatment approach.
April 2026 in “International Journal of Molecular Sciences” This review synthesizes recent research on how Wnt signaling regulates skin, hair follicle, and nail regeneration, highlighting its compartment-specific roles and discussing targeted strategies for treating conditions like alopecia, chronic wounds, and skin cancer.
This study found that a bioorthogonal microneedle patch delivering AAV-aFGF effectively improved hair follicle regeneration and sustained hair growth in murine alopecia models compared to other methods.
August 2024 in “International Journal of Molecular Sciences” In this animal study, researchers found that local administration of mesenchymal stem cell therapy improved hair regrowth and reduced local inflammatory cytokines in mice with Alopecia Areata, although systemic cytokine levels were unchanged.
November 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that disrupted cholesterol homeostasis impairs hair regrowth in individuals with primary cicatricial alopecia by damaging hair follicle stem cells, highlighting the importance of cholesterol in maintaining stem cell function and hair follicle integrity.
May 2023 in “Plastic and reconstructive surgery. Global open” This study reviewed 29 clinical studies on autologous activated PRP injections for alopecia and found that 27 studies reported significant improvements in hair density, regrowth, and reduction in hair loss, demonstrating potential effectiveness as a treatment for hair loss.
November 2021 in “CRC Press eBooks” This article reviews anagen effluvium, a type of non-scarring alopecia that affects both men and women, often induced by chemotherapy or radiation, and discusses diagnostic approaches but reports no new clinical findings.
January 2011 in “Medicina interna de México” This article explains the characteristics, diagnosis, and causes of telogen effluvium hair loss but reports no new clinical findings.
January 2006 in “Advances in developmental biology” This review discusses the roles of the hairless (HR) protein as a corepressor, particularly its impact on RORα-mediated transcriptional repression, and reports no new experimental findings.
January 1996 in “Springer eBooks” Hair can regrow if the sebaceous gland is intact, even if the hair root is removed.
57 citations
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November 1998 in “Wound Repair and Regeneration” This research observed that dermal papilla cells have the potential to regenerate hair bulbs under preferred environmental conditions when associated with dermal sheath cells or exposed to specific growth factors.
January 2026 in “Dermatologic Therapy” This study found that Pinus massoniana needles extract may promote hair regrowth in a mouse model of androgenetic alopecia, potentially by reducing oxidative stress and affecting immune, metabolic, and apoptosis-related pathways.