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Surgical therapies for vitiligo vary in effectiveness, with combination therapy and medical tattooing recommended for better results.

The document concludes that better targeted treatments are needed for wound healing, and single-cell technologies may improve cell-based therapies.

The document concludes that skin stem cells are important for hair growth and wound healing, and could be used in regenerative medicine.

The document concludes that understanding how the skin's immune system and inflammation work is complex and requires more research to improve treatments for skin diseases.

Changing the environment around stem cells could help tissue repair, but it's hard to be precise and avoid side effects.

Understanding gene expression in hair follicles can reveal insights into hair growth and disorders.

Understanding phenotypic plasticity is crucial for developing effective cancer therapies.

Changing how mesenchymal stromal cells are grown can improve their healing abilities.

Epithelial-mesenchymal interactions control hair growth cycles through specific molecular signals.

TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.

Fat cells help recruit healing cells and build skin structure during wound healing.

The document concludes that understanding hair follicle biology can lead to better hair loss treatments.

Eph receptors and ephrins may be promising targets for treating diseases, but more understanding is needed for effective and safe therapies.

Biomaterials with MSC-derived substances could improve tissue repair and have advantages over direct cell therapy.

Skin fat cells help with skin balance, hair growth, and healing wounds.

Certain cells from hair follicles can create new hair and contribute to hair growth when implanted in mice.

Scientists made working salivary glands in mice using bioengineered cells, which could help treat dry mouth.

Bioprinting could improve wound healing but needs more development to match real skin.

The document concludes that more research is needed to better understand and treat primary cicatricial alopecias, and suggests a possible reclassification based on molecular pathways.

The dermal papilla is crucial for hair growth and health, and understanding it could lead to new hair loss treatments.

Understanding different types of skin cells, especially fibroblasts, can lead to better treatments for wound healing and less scarring.

Cathepsin L is essential for normal hair growth and development.

Skin aging is due to impaired stem cell mobilization or fewer responsive stem cells.

The document concludes that specific cells are essential for hair growth and more research is needed to understand how to maintain their hair-inducing properties.

Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.

Damage to skin releases dsRNA, which activates TLR3 and helps in skin and hair follicle regeneration.

The skin's internal clock affects healing, cancer risk, aging, immunity, and hair growth, and disruptions can harm skin health.

The document concludes that while significant progress has been made in understanding skin biology and stem cells, more research is needed to fully understand their interactions with their environment.

Macrophages help regrow hair by activating stem cells using AKT/β-catenin and TNF.

PDGFA/AKT signaling is important for the growth and maintenance of certain skin fat cells.