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Finasteride reduces scalp DHT levels, potentially treating male pattern baldness.

A49T gene variant linked to higher prostate cancer risk, lower hormone levels, and slightly reduced balding risk.

LY191704 is a compound that effectively blocks a specific enzyme involved in hormone conversion and could help treat enlarged prostate and hair loss.

5α-reductase inhibitors and alpha-1 adrenergic antagonists together effectively treat benign prostatic hyperplasia, with long-term benefits.

Using finasteride or dutasteride may cause long-lasting erectile dysfunction.

Selective non-steroidal inhibitors of 5α-reductase type 1 can help treat DHT-related disorders.

Long-term finasteride use doesn't change bone density or metabolism.

5α-reductase inhibitors, like finasteride and dutasteride, effectively treat BPH, male baldness, and hirsutism, with potential for acne and prostate cancer prevention.

Male hormones affect oil-producing skin cells differently based on their body location, and the drug spironolactone can reduce these effects.

Lygodii Spora extract may help treat hair loss by blocking a hair loss-related enzyme and promoting hair growth.

PNU157706 reduced rat sperm movement and fertility without affecting offspring health.

Curcuma aeruginosa extract combined with minoxidil effectively treats male-pattern baldness.

Finasteride and minoxidil together promote hair growth better than either alone.

Chitosan-coated nanoparticles improve skin delivery of hair loss treatments with fewer side effects.

Finasteride effectively treats male hair loss, improving growth and density.

5-alpha-reductase inhibitors may cause a low incidence of erectile dysfunction that decreases over time.

Rats had lasting erectile problems after stopping a certain medication.

Exercise improves insulin sensitivity and hormone regulation in PCOS rats.

Finasteride reduces dihydrotestosterone, increases testosterone, and may treat hirsutism in women.

Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

Higher enzyme levels found in women with hair loss, suggesting hormone imbalance.

Progesterone byproduct 5αP stimulates mammary tumor growth, but finasteride can suppress it.

5α-Reductase inhibitors can help treat hair loss, acne, and prostate issues by reducing DHT levels.

The gene SDR5A1 is found in scalp hair of both hirsute and normal individuals, but it does not explain differences in hair growth.

Finasteride effectively treats enlarged prostate and male baldness, improves symptoms of hirsutism in women, but doesn't work for acne, and may delay prostate cancer progression with few side effects.

Some hair loss and prostate drugs might increase the risk of diabetes and heart disease.

Finasteride doesn't affect erections much, but may decrease libido in men.

Blocking 5α-reductase can harm memory and brain structure, and increase harmful brain changes in male mice used for Alzheimer's disease research.

Natural herbal compounds might treat certain medical conditions by reducing DHT levels, but more research is needed to confirm their effectiveness and safety.

Female mice with disrupted 5α-reductase 1 had significant metabolic issues, including stress response problems, insulin resistance, liver fat buildup, and obesity.