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GLP-1 receptor agonists help with weight loss but need to be combined with other treatments for best results.

Adult acne is often related to hormonal disorders, especially in women, and may need long-term treatment involving specialists.

Bariatric surgery may help severely obese teenagers but has risks and requires careful patient selection and long-term care.

Testosterone therapy improves physical function, strength, and body composition in older men with low testosterone levels.

MK-0773 safely increased muscle mass but did not improve muscle strength or function in elderly women with sarcopenia.

Higher testosterone levels can increase the risk of certain diseases like type 2 diabetes in women and prostate cancer in men, but can also protect against autoimmune diseases and hair loss. It also affects body fat and bone density.

Resistance training might help with PCOS symptoms, but more research is needed.

Chromium salts may help with insulin sensitivity in PCOS, but more research is needed to confirm their overall effectiveness and safety.

Daughters of women with PCOS generally experience normal puberty but may have more body hair and different body fat distribution.

Testosterone and its metabolites have varied effects on different body systems, especially during puberty.

The foreword introduces a medical issue discussing male hormonal health, treatments, and the effects of conditions like obesity and aging.

The safety and effectiveness of gender-affirming treatments for children are uncertain, with potential long-term risks like infertility.

Testosterone therapy can improve sexual function in women but long-term safety is unclear.

Gynecologists should provide comprehensive care for transgender patients, including mental health evaluation, hormone therapy, and surgical options, while monitoring for side effects and ensuring patient safety.

Scientists have developed a new method to detect steroid abuse in athletes using cell-based tests, which could be the future of anti-doping methods.

A combination of nanomilled oral testosterone and dutasteride normalized testosterone levels in men with low testosterone and is safe for short-term use.

The same hormone can affect gene expression differently in various tissues, which could lead to new treatments for conditions like hair loss.

Transgender patients in critical care need better-trained medical staff and specific guidelines.

Insulin sensitizers may slightly reduce hirsutism but are less effective than other treatments.

Metabolic syndrome and PCOS are related but separate conditions, with metabolic syndrome increasing the risk of heart disease and diabetes.

PCOS in lean women is a serious health condition with implications beyond fertility, affecting metabolism and increasing cardiovascular disease risk.

Resistance training improved BMI and menstrual regularity more in women with PCOS than aerobic training.

A model using hormone levels, cycle length, and BMI can help identify PCOS in Chinese women but isn't for screening teens.

People with PCOS have higher levels of PAI-1, which may increase their risk of heart disease and fertility issues.

Metformin helps improve symptoms and reproductive outcomes in people with polycystic ovary syndrome.

GLP-1 receptor agonists, like Dulaglutide, Liraglutide, and Semaglutide, have potential benefits beyond the pancreas, including neuroprotection, pain suppression, cardiovascular protection, obesity management, and cancer treatment, but there are concerns about pancreatitis and pancreatic cancer risks.

Skin problems like acne and excess hair in PCOS are common and linked to being overweight.

Nonobese, normotensive Indian women with PCOS may have a higher risk of heart problems linked to inflammation and insulin resistance.

Deoxycholic acid effectively reduces double chin fat with temporary side effects and high patient satisfaction.

Metformin combined with lifestyle changes improves insulin resistance and reduces testosterone levels in women with PCOS more than lifestyle changes alone.