Assessing the Efficacy of Deoxycholic Acid for the Treatment of Submental Fat: A Three-Dimensional Study

The study evaluated the effectiveness of deoxycholic acid in treating submental fat in 13 patients, using 3D volumetric analysis and patient satisfaction scores. Results indicated a significant reduction in submental volume after an average of 3.4 treatment sessions, with a temporary volume increase during recovery. Patients reported improved satisfaction, despite experiencing self-resolving paresthesia, and no major complications were observed. The study concluded that deoxycholic acid is an effective treatment for submental adiposity, with objective measurements aligning with patient-reported outcomes. Side effects were noted to decrease over time, and the study highlighted the importance of patient selection. However, the small sample size was a limitation, suggesting the need for larger studies to better understand potential serious adverse events.