January 2017 in “Journal of Cosmetics, Dermatological Sciences and Applications” Among Chinese women, this study observed that hair density decreases and scalp erythema increases with age, with most aging features like hair diameter and sebum content peaking in their 40s.
October 2024 in “Journal of the Endocrine Society” This case report highlights that a patient with resistance to thyroid hormone was misdiagnosed as having Graves’ disease, leading to unnecessary radioactive iodine treatment.
COVID-19 might cause gray hair to regain color.
30 citations
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January 2009 in “Nuclear Receptor Signaling” This study identified the Hairless (Hr) gene-encoded protein as a corepressor that plays a crucial role in maintaining skin and hair by regulating epithelial stem cell differentiation and gene expression via chromatin remodeling, which may impact both development and disease.
November 2025 in “Zenodo (CERN European Organization for Nuclear Research)” This review explores the causes and management of premature greying in children, noting it may indicate underlying health issues, and emphasizes structured evaluations and treatments, particularly for nutritional deficiencies and hypothyroidism, to address hair depigmentation.
November 2025 in “Zenodo (CERN European Organization for Nuclear Research)” This review highlights concerns around premature greying in children, detailing possible links to nutritional deficiencies and other health issues, and emphasizes that structured evaluation and targeted treatment may aid in reversing the condition.
This study found that Heated radish extract potently suppressed melanin production in vitro and reduced wrinkle formation and collagen degradation in vivo, suggesting its potential as a skin whitening and antiaging product.
20 citations
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August 1981 in “Developmental Medicine & Child Neurology” 13 citations
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June 1981 in “Developmental Medicine & Child Neurology” 2 citations
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August 2024 in “Indian Dermatology Online Journal” Premature graying of hair is mainly caused by genetics, stress, and environment, with potential treatments being explored.
1 citations
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July 2018 in “JAMA dermatology” This abstract contains navigation and subscription information for JAMA Dermatology and reports no new clinical findings.
December 2021 in “Australasian Journal of Dermatology” This study reported cases of post-COVID-19 telogen effluvium in patients who also exhibited distinctive red band changes in their nails.
1 citations
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October 1993 in “PEDIATRICS” This article recounts a series of "hair burning syncope" cases in black girls experiencing seizures during hair grooming with hot irons, without presenting new research findings.
5 citations
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January 2018 in “Acta dermato-venereologica” This study identified an association between premature hair greying and larger waist circumference among young healthy subjects.
September 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” This study applied a new RGB trichrome stain to human skin samples, revealing distinct structural staining in normal tissues and potential proteoglycan-rich zones in hair follicles.
October 2019 in “European Journal of Dermatology” This review discusses the diagnosis and treatment of pityriasis rubra pilaris and reports no new clinical results.
10 citations
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February 2008 in “Photochemistry and photobiology” This study suggests that the vitamin D receptor and hairless gene may directly regulate each other via a transcriptional mechanism, potentially explaining phenotypic similarities between atrichia and VDRRIIa rickets.
77 citations
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August 1986 in “Archives of Dermatology” This report describes a case in which intramuscular cyanocobalamin treatment reversed skin and nail pigmentation changes and premature gray hair caused by vitamin B12 deficiency due to pernicious anemia.
This study on Antirrhinum trichomes found that stickiness in A. hispanicum is due to a recessive allele and mapped it to a specific region on Chromosome 1, while baldness in A. siculum likely involves a novel hairy allele.
6 citations
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May 2012 in “Archives of Dermatological Research” This study reports a novel missense mutation in the HR gene in a 68-year-old Hungarian woman with alopecia universalis and limb deformities, suggesting a need for further research on its role in these conditions.
9 citations
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June 1959 in “Archives of dermatology” This article discusses the importance of integrating clinical observations with laboratory research, emphasizing the need for clinicians to collaborate with researchers to address medical problems.
May 2019 in “Journal of clinical oncology” This study found that concurrent chemotherapy with radiotherapy may increase the risk of grade 2 persistent radiation-induced alopecia, while topical minoxidil showed potential benefits, though more research is needed on its efficacy.
October 2024 in “Photodermatology Photoimmunology & Photomedicine” In this study, participants with androgenetic alopecia who used an LED helmet emitting red and green light experienced significant improvements in hair growth measures, with red light showing superior results in increasing hair diameter and reducing vellus hair density over 6 months.
January 1957 in “Nihon Chikusan Gakkaiho” This article examines microscopic structural differences and pigment distribution in various rabbit hair colors and reports no clinical results.
36 citations
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November 2016 in “European journal of dermatology/EJD. European journal of dermatology” This review examines systemic drugs that can cause changes in hair color and emphasizes the importance of reporting these adverse events, but it does not include new clinical outcomes.
35 citations
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April 1993 in “Clinics in dermatology” Rosacea is a common skin condition mainly causing facial redness.
November 2025 in “World Journal of Biology Pharmacy and Health Sciences” This review reported that premature greying in children, which can indicate certain deficiencies or disorders, may be addressed through a structured evaluation and treatment targeting factors like vitamin B12 and iron deficiencies or hypothyroidism, providing a practical approach for pediatric care.
15 citations
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November 2017 in “JAAD Case Reports” This study reports no known changes in hair pigmentation associated with brentuximab vedotin, despite its various other documented adverse effects.
May 2023 in “Health science reports” This review discusses the harmful effects of coloring shampoos containing trihydroxybenzene on the scalp-skin barrier and emphasizes the need for safer ingredient selection to prevent side effects.
August 2019 in “Research Square (Research Square)” This study found that exposure to red LED light may improve fibre quality and hair follicle development in Angora rabbits, potentially due to increased melatonin secretion.