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In this report, a unique case of premature graying in a 32-year-old male, with onset at age 15 and a distinctive fractal pattern, was presented, highlighting the need for further investigation into its potential causes and mechanisms.

Stress can cause hair to turn gray by depleting stem cells.

This study describes GPRC5D's unique expression pattern in tissues that produce hard keratin, with retinoic acid inducing its expression in hair bulb cells and affecting keratin gene regulation.

This study observed a significant rise and fall in black hair dye dermatitis cases over six years, primarily affecting middle-aged men, with most cases presenting as chronic pigmented lichenoid photodermatitis.

This study describes a patient with hereditary vitamin D resistant rickets (HVDRR) who, despite having a truncated vitamin D receptor, did not exhibit typical hair or skin abnormalities, suggesting possible compensation via interactions with other proteins.

Iron supplements can restore normal hair color in cases of premature graying linked to iron deficiency.

This article reports on a rare case of hair yellowing induced by topical minoxidil use and discusses drug-induced hair color changes.

This review discusses the mechanisms of hair repigmentation and reports no clinical results; the authors suggest further research into topical treatments for reversing gray hair.

This study suggests that long-term use of hair dyes may be associated with higher testosterone levels among premenopausal Japanese women.

Blond hair in Solomon Islanders is due to a unique genetic variant, not European ancestry.

This study found that varied hair colors influence body image by creating different perceptions, such as charisma and friendliness, with specific colors like red and black producing strong image effects.

This case report describes three Iranian men with gradual reddish-brown pigmentation on their cheeks and preauricular areas since childhood, unresponsive to sunblocks and topical steroids.

Iron deficiency might be linked to hair loss, but more research is needed.

Vitamin D3 and its receptor are important for hair growth, and understanding receptors could help treat hair graying and skin cancer.

This review discusses various aspects of hair color, including its formation and evolutionary variations, based on research presented at the 4th Intercontinental Meeting of Hair Research Societies 2004, without providing new experimental results.

This review discusses the roles of the hairless (HR) protein as a corepressor, particularly its impact on RORα-mediated transcriptional repression, and reports no new experimental findings.

This study in mice found that maternal iron deficiency led to hair loss and growth abnormalities in offspring due to increased oxidative stress and disrupted signaling pathways, but postnatal iron supplementation was able to reverse these effects.

This study found that individuals with premature graying of hair in India had significantly lower levels of serum ferritin, vitamin B12, and vitamin D3 compared to controls.

In this study, silencing P-cadherin in human scalp hair follicles reduced melanogenesis and associated protein expression, suggesting P-cadherin is crucial for normal hair pigmentation via GSK3β-mediated Wnt signaling.

This study suggests that elevated copper levels in domestic tapwater, exacerbated by its aggressive properties, likely contribute to green hair by damaging the cuticle and increasing copper uptake.

This study found that white hair exhibits increased expression of genes and proteins linked to active hair growth compared to black hair, suggesting that hair greying is associated with enhanced hair growth activity.

This study found that oxidative stress in hair follicle melanocytes contributes to premature aging and apoptosis, providing insights into graying as a model for studying aging and testing antiaging therapies.

This case study describes an uncommon variant of coudability hair in alopecia areata, where intermittent inflammatory processes result in alternating bands of lighter color and reduced hair shaft calibre.

This study found that non-pigmented hair follicles have significantly lower expression of nucleotide excision repair genes, which may be associated with reduced melanin production capacity in these follicles.

This study found that genipin-based pigments, accelerated by riboflavin and blue-light photocatalysis, achieved commercial-level hair dye results with enhanced gloss and excellent color retention while reducing cuticle disruption, offering a potentially safer and faster alternative to traditional hair coloration methods.