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Scientists successfully created and analyzed the structure of a part of the human androgen receptor with specific modulators and a peptide to understand how it binds differently in various tissues.

The vitamin D receptor helps maintain hair and bone health even without binding vitamin D.

New findings explain how genetic changes, body clocks, and certain molecules affect tissue response to stress hormones.

PF-05314882 selectively activates androgen receptors without much effect on prostate and may help in prostate cancer treatment and hair loss prevention.

Fibroblast growth factor receptor signaling controls cell development and repair, and its malfunction can cause disorders and cancer, but it also offers potential for targeted therapies.

Blocking Wnt/β-catenin signaling with EGF receptor is necessary for proper hair growth.

Mice without the vitamin D receptor have bone issues and other health problems, suggesting vitamin D is important for preventing various diseases in humans.

The vitamin D receptor is involved in multiple body functions beyond calcium regulation, including immune response and rapid reactions not related to gene activity.

The vitamin D receptor has many roles in the body beyond managing calcium, affecting the immune system, hair growth, muscles, fat, bone marrow, and cancer cells.

The androgen receptor's shape-changing ability helps it function but can lead to cancer treatment resistance.

Compounds from the Sansevieria trifasciata plant might be effective for treating hair loss.

Targeting the Smoothened receptor shows promise for treating certain cancers.

EGF and KGF signalling prevent hair follicle formation and promote skin cell development in mice.

Some vitamin D analogs can thicken skin and reduce pore size like a common acne treatment, with one analog also affecting skin growth factors.

A peptide known for reducing wrinkles also effectively inhibits an enzyme linked to skin inflammation and acne.

The research explains how a human enzyme binds and processes its substrate, which could relate to its role in biological functions and hair loss.

New compounds with carborane showed anti-androgen effects similar to flutamide.

We need better ways to test and understand SARMs to make safer and more effective treatments.

Etifoxine, an anxiety drug, can lessen brain inflammation and cognitive issues in mice, partly by increasing production of protective brain steroids.

Male hormones and their receptors play a key role in hair loss and skin health, with potential new treatments being explored.

Mutations in certain receptors can cause diseases and offer new treatment options.

Scientists have developed a new method to detect steroid abuse in athletes using cell-based tests, which could be the future of anti-doping methods.

The Androgen Receptor could be a target for treating diseases like cancer, but more research is needed to confirm the effectiveness of potential treatments.

A compound from Calophyllum inophyllum L. leaf may help treat non-small cell lung cancer.

People with alopecia areata often have lower vitamin D levels, which are linked to more severe and longer-lasting hair loss, but vitamin D receptor levels in the skin don't show the same pattern and don't predict treatment success.

Understanding drug interactions, side effects, and patient-specific factors is crucial for effective dermatological care.

The document concludes that targeting 5α-reductase, the androgen receptor, and hair growth genes, along with using compounds with anti-androgenic properties, could lead to more effective hair loss treatments.

Androgen receptors are active in many tissues of both male and female mice, not just reproductive organs.

L-PGDS has specific binding sites for its functions and could help in drug delivery system design.

Changing the environment around stem cells could help tissue repair, but it's hard to be precise and avoid side effects.