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This study reported that prompt diagnosis and treatment with 5-alpha-reductase inhibitors and topical immunomodulators are key to mitigating the effects of frontal fibrosing alopecia and preventing permanent hair loss.

This study developed a simple HPLC method for accurately estimating tamsulosin and finasteride in pharmaceutical forms, demonstrating good precision and potential application in combined dosage analysis.

This review discusses the role of mTOR kinase in pulmonary fibrosis and explores how mTOR inhibitors may help slow the progression of this condition, but it reports no new results.

RADA16-I can effectively deliver and release mangiferin, improving its solubility and bioavailability.

This study used a newly developed RP-HPLC method to accurately measure finasteride distribution in human cadaver skin after applying different vesicular drug delivery systems.

Finasteride may reduce heart damage in rats.

In this study, a 75% ethanol extract of Fructus Psoraleae was found to significantly inhibit 5-α reductase and promote hair growth in mice, indicating its potential as a treatment for androgenetic alopecia through modulation of the Nrf2-Keap1 pathway.

This study found that finasteride use was associated with significantly higher odds of obstructive sleep apnea and insomnia compared to other medications.

This study reports a new method for selectively synthesizing finasteride Form-I in good yield using water as an ecofriendly solvent at room temperature.

This study develops FR-1, a topical small molecule, which reduces scarring and avoids skin atrophy in a murine wound model, showing potential for treating fibrosis without the side effects of current therapies.

This narrative review explores the failure of fludalanine as an orally active antibiotic and highlights valuable insights into problem-solving strategies in drug discovery, without reporting new clinical results.

This study reported that fibrosing alopecia in a pattern distribution can occur in patients of color, with clinical and histopathological features allowing for an accurate differential diagnosis.

This study found that FLASH radiation within a Spread-out Bragg Peak retained its normal tissue-sparing effect compared to conventional radiation, with a 40% reduction in acute skin damage and an 18% reduction in fibrotic development in mice.

This article reviews cell proteomic footprinting technology and its application in improving the authentication and quality control of cell-based immunotherapeutics, without providing new clinical results.

This study identified Azithromycin and Roxithromycin as novel senolytic antibiotics that effectively target and reduce senescent human fibroblast cells.

This review discusses the role of mTOR signaling in the epidermis, emphasizing its importance in skin processes like barrier formation and wound repair, and reports no new experimental results.

This study proposes that mammalian target of rapamycin (mTOR) may connect various signaling pathways in hair follicle tumor formation, offering a potential unified model for understanding these tumors.

This study successfully established Tsc2-deficient embryonic stem cells from Eker rats and found these cells have distinct gene expression compared to non-mutant cells, which could help identify new therapeutic targets for TSC-related pathogenesis.

This study suggests that both the sebum composition and microbial imbalance on the scalp may play a role in the development of androgenetic alopecia among Japanese males.

In this study, the researchers reported a new case of Hutchinson-Gilford progeria syndrome with a novel LMNA mutation and successful surgical intervention for airway obstruction.

In this case report, two female patients with refractory systemic lupus erythematosus showed significant improvement after treatment with the JAK inhibitor upadacitinib, indicating potential as a promising option for difficult cases, although further research is needed to confirm its broader safety and efficacy.

This case report highlights a rare instance of erosive pustular dermatosis of the scalp in a patient on afatinib, underlining the importance of early recognition and management of this adverse effect.

In this study, researchers found that RORA directly regulates the expression of the Bnip3 gene, which is crucial for hair follicle stem cell health, using rat HFSCs as a model. They propose that targeting RORA could modulate HFSC status.

This study identified a specific hemizygous intronic variant in the MBTPS2 gene associated with IFAP syndrome in a patient, revealing exon skipping and reduced normal transcript expression through long-read RNA sequencing.

This review discusses recent research and applications of RADA16 and RADA16-based peptide scaffolds in biomedicine, including their roles in tissue repair and drug delivery, but reports no new clinical results.

This study demonstrated that FT-Raman spectroscopy is effective for identifying finasteride polymorphs in tablets and detecting the presence of alternative polymorphs down to about 15% concentration.

Fibrosing alopecia in a pattern distribution is a unique hair loss condition with inflammation and scarring, resembling but distinct from common balding.

In this study, polymeric micelles containing retinoic acid were found to improve targeted delivery to hair follicle structures in human skin more efficiently than a marketed retinoic acid gel, suggesting potentially safer and more effective acne treatment.

This study developed and validated three analytical techniques for the simultaneous quantification of Finasteride and Tamsulosin Hydrochloride in pharmaceutical dosage forms, with proven accuracy and precision.