November 2023 in “JEADV Clinical Practice” In this study, adults with severe alopecia areata experienced greater improvements in hair regrowth, health-related quality of life, and reduced anxiety and depression symptoms after 36 weeks of treatment with baricitinib compared to placebo.
This trial will compare the effectiveness of spironolactone to doxycycline for treating acne in adult females, potentially offering an alternative to antibiotics and isotretinoin.
31 citations
,
June 2018 in “Dermatologic Surgery” In this randomized, double-blind trial, researchers observed that low-level laser therapy led to significantly greater hair regrowth on treated areas compared to a sham treatment in patients with androgenetic alopecia over 24 weeks, suggesting it as a potentially effective and safe option.
6 citations
,
June 2021 in “EClinicalMedicine” In this study, ALRV5XR significantly increased hair regrowth in women with androgenetic alopecia or telogen effluvium, with no adverse events reported.
October 2023 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” Using both minoxidil and finasteride together on the scalp works better for male hair loss than using either one alone.
December 2014 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” Low-level light therapy significantly increased hair density and thickness in people with hair loss, but they didn't notice a difference.
February 2007 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” Taking 1mg of finasteride daily for hair loss can lower PSA levels by 40-50%, so to keep PSA effective as a cancer screening tool, the PSA value should be doubled during treatment.
14 citations
,
September 2023 in “Frontiers in Nutrition” This source observed that while supplementation with pro-, pre-, and synbiotics showed some beneficial effects for PCOS-related outcomes, the evidence quality was deemed low to very low, highlighting the need for further well-designed randomized controlled trials in women with PCOS.
May 2026 in “Journal of the American Academy of Dermatology” In this study, sublingual minoxidil was found to be a safe and effective treatment for increasing hair growth in transgender individuals with mild androgenetic alopecia who are undergoing full-dose testosterone therapy.
April 2024 in “Anais brasileiros de dermatologia/Anais Brasileiros de Dermatologia” Using both minoxidil and biotin together increased hair growth more than using either one alone.
September 2022 in “Research Square (Research Square)” This study found that while pro-, pre-, and synbiotics may have beneficial effects on certain PCOS-related outcomes, the certainty of this evidence is low to very low.
55 citations
,
July 2020 in “International Wound Journal” This study evaluated the feasibility of a single-center, three-arm trial to assess fat grafting with or without PRP for diabetic foot ulcers, finding high patient engagement and indicating that a multi-center trial could be safe and feasible.
17 citations
,
February 1989 in “Fertility and sterility” In this study, cimetidine at a daily dose of 1.5 gm for 3 months did not significantly affect hair growth in women with moderate to severe hirsutism.
9 citations
,
November 2021 in “PubMed” This study found that FDA-approved low-level light/laser therapy devices significantly increased hair density in individuals with pattern hair loss compared to sham devices.
4 citations
,
August 2020 in “Facial plastic surgery & aesthetic medicine” This study found that combining concentrated growth factor injections with minoxidil treatment significantly improved hair growth and participant satisfaction in male patients with androgenetic alopecia compared to minoxidil alone.
3 citations
,
November 2005 in “Journal of Research in Medical Sciences” This study found that six months of using finasteride cream 0.5% did not significantly change the number or thickness of facial hair in women with hirsutism, although patients felt hair growth slowed.
1 citations
,
September 2024 in “Dermatological Reviews” In this systematic review, significant improvements in clinical severity, patient-reported outcomes, and quality of life were reported for dupilumab compared to placebo in patients with moderate-to-severe atopic dermatitis, prurigo nodularis, and alopecia areata, supporting its efficacy and safety for these dermatological conditions.
1 citations
,
September 2023 in “Journal of the American Academy of Dermatology” This study focused on baricitinib's effect on patients with severe alopecia areata, highlighting its efficacy for hair regrowth and its potential to improve health-related quality of life and psychological symptoms, as seen in two phase 3 trials.
February 2026 in “Trials” This abstract describes a clinical trial registered in the Chinese Clinical Trial Registry, with its first participant enrolled on September 30, 2024; no specific study outcomes are reported.
February 2026 in “Trials” The Exfoliate-Dissolve-Repair skincare approach may effectively treat keratosis pilaris and reduce the need for corticosteroids.
January 2026 in “AIMS Public Health” This abstract describes the approval of a study by the Japan Registry of Clinical Trials and the North South University Institutional Review Board, but it does not report any results or conclusions.
June 2024 in “The Open dermatology journal” In this study, researchers reported that an herbal extract with dihydroquercetin glucoside, epigallocatechin gallate glucoside, zinc, and glycine showed similar effectiveness and safety to minoxidil in treating androgenetic alopecia over 24 weeks, with no significant differences in hair growth outcomes between the groups.
This study reported that treating PCOS with Karunjchirakam Chooranam showed significant improvements in various cases, suggesting it may be effective for early intervention and prevention of complications.
68 citations
,
April 2002 in “Journal of Alternative and Complementary Medicine” This study suggests that botanical 5AR inhibitors like Serenoa repens and β-sitosterol may improve symptoms of androgenetic alopecia, with 60% of treated subjects showing improvement compared to placebo.
65 citations
,
April 2002 in “Journal of Alternative and Complementary Medicine” This study found that 60% of men with mild to moderate androgenetic alopecia showed improvement after treatment with botanically derived 5AR inhibitors, suggesting these compounds may be effective, though larger trials are needed.
9 citations
,
January 2007 in “Journal of dermatological treatment” This study found that applying 2.5% testosterone gel increased facial terminal hairs in young males with beta-thalassemia major and was well tolerated.
August 2026 in “International Journal of Stem Cells” In this study, Korean adults with damaged hair who took 3g/day of low-molecular-weight collagen peptide GT for 24 weeks showed significant improvements in hair gloss, elasticity, and scalp elasticity compared to placebo, without any adverse events.
May 2026 in “Journal of Functional Foods” In this study of women with polycystic ovary syndrome, 12 weeks of daily ginger supplementation significantly reduced total testosterone and improved menstrual irregularities compared to placebo, suggesting potential as a natural therapeutic approach, although larger studies are needed.
August 2023 in “Skin Research and Technology” In this clinical trial, oral consumption of a persimmon leaf extract-containing complex significantly increased hair density and thickness over 24 weeks compared to a placebo, although improvements in hair gloss were not statistically significant.
January 2019 in “Journal of cosmetology & trichology” In this study, researchers found that supplementation with L-cystine, either alone or with a keratin hydrolysate, significantly improved hair density, hair and nail brightness, and nail growth in women experiencing acute telogen effluvium and brittle nail syndrome over three months.