Improvements in Health-Related Quality of Life and Psychological Symptoms in Patients With Severe Alopecia Areata Achieving Scalp Hair Regrowth: Results From Two Randomized Controlled Trials

    September 2023 in “ Journal of the American Academy of Dermatology ”
    Brittany G. Craiglow, Yang Won Lee, Sergio Vañó‐Galván, Alexander Egeberg, Yves Dutronc, Frédérick Durand, Evangeline Pierce, Yuxin Ding, Yunfei Chen, Arash Mostaghimi
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    TLDR Baricitinib helps regrow hair and improves quality of life and mental health in severe alopecia areata patients.
    The document reports on two phase 3 randomized controlled trials (BRAVE-AA1/2) that evaluated the efficacy of Baricitinib in patients with severe alopecia areata (AA). The trials demonstrated that Baricitinib significantly improved scalp hair regrowth. Additionally, these improvements were associated with enhanced health-related quality of life (HRQoL) and reduced psychological symptoms in the patients. The study underscores the importance of addressing both physical and psychological aspects in the treatment of severe AA. The research was fully sponsored by Eli Lilly and Company.
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      In this conversation, 4990 discussed various treatments for hair loss, including oral minoxidil, PRP, transplan, Jak inhibitors, Dutasteride, Finasteride, Olumiant, Ketoconazole, RU58841, microneedling, baricitinib, and CCCA. They recommended scalp biopsies in unclear cases of DUPA, twice weekly to twice daily shampooing for topical minoxidil users, and two sessions spaced one month apart with follow up at month three to determine the effectiveness of PRP treatment.

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      in Chat  34 upvotes 2 months ago
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      community Should I get transplant #4 or just shave my head?

      in Transplants  170 upvotes 4 months ago
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