Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This article reviews R-Spondin-1's complex role in various skin conditions, emphasizing its diagnostic, prognostic, and potential therapeutic applications.

This study identifies a mechanism where dsRNA activates TLR3 to induce RA production, promoting hair follicle regeneration in mice and suggesting a potential role in human tissue regeneration.

This review discusses the potential esthetic applications and regenerative properties of adipose-derived stem cells but reports no new clinical findings, emphasizing the need for further research to establish efficacy.

This study suggests that dermal stem/progenitor cells can be enriched by intracellular granularity and display high proliferation and differentiation potential in vitro, distinguishing them from other fibroblasts and progenitors.

Adding stem cells to fat grafts for facial rejuvenation might improve outcomes, but more research is needed to confirm safety and effectiveness.

This study using scRNA-seq on 96 skin biopsies from 51 healthy individuals revealed distinct cell signaling pathways in different skin sites, including unique pathways in facial and palmoplantar skin, which may explain their varying susceptibilities to skin disorders.

This study identifies a new mutation in the Scd1 gene in a strain of Kunming mice, causing skin and hair defects with the mildest impact among similar mutations.

This study established a murine chronic graft-versus-host disease model with scleroderma features, showing typical skin changes and cellular infiltrates associated with the condition.

This study found that dysregulation of the DNA damage response in stem cells is a common factor of aging, affecting tissues like the skin, brain, kidneys, and intestine.

This article reviews advancements in carbon dots for tissue engineering and regenerative medicine, highlighting challenges and future directions without presenting new clinical findings.

In this study, researchers used NIR-II fluorescence imaging to track the survival and migration of EPI-NCSCs in rat models, finding that these stem cells aided in repairing facial nerve defects when applied via acellular nerve allografts.

This study found that RSPO1 mutations in patients with a 46XX disorder of sexual development contribute to impaired skin integrity and increased risk of squamous cell carcinoma in areas subject to friction.

This review discusses the potential of adipose-derived stem cells for regenerative medicine, highlighting their ability to differentiate, secrete factors, and modulate the immune response, but reports no new findings.

This review discusses autologous dermis-derived stem cells and their potential in regenerative medicine, summarizing current literature on their niches, characteristics, and applications, but it reports no new experimental results.

This tool was developed to enhance reproducibility and sensitivity in measuring partial hair regrowth in alopecia areata patients, particularly those undergoing JAK inhibitor therapy, using scalp photographs.

This study found that adipose‐derived stem cells can restore skin barrier function and inhibit photoaging-related responses in UVB-irradiated mice, suggesting a potential therapeutic role in managing skin photoaging.

This study reports that adipose-derived stem cells can protect against radiation-induced dermatitis in rats by reducing apoptosis through lowering Cathepsin F expression, suggesting a potential new therapeutic approach.

This study found that using induced pluripotent stem cell-derived mesenchymal stem cells with acellular nerve allografts significantly improved axon regeneration and functional recovery in rats with sciatic nerve injuries, suggesting a promising approach for clinical nerve repair therapies.

This study found that disrupting Sdf1-Cxcr4 signaling promoted tissue regeneration in wild-type mice, hinting at potential strategies to induce such regeneration in mammals.

This study classified scars in discoid lupus erythematosus patients into six types based on anatomical location and morphology, suggesting early identification might influence more aggressive treatment strategies.

In this animal study, ginsenoside Rb1 demonstrated therapeutic effects on hypertrophic scar remodeling, with the highest efficacy observed at a dose of 0.56 mg.

This study identifies unique gene expression patterns in specialized fibroblasts within adult hair follicles, which advances understanding of their role in tissue regeneration.

This study observed that exosomes derived from adipose-derived stem cells significantly enhanced bone marrow mesenchymal stem cell migration and osteogenesis, leading to improved bone regeneration in a rat model of calvarial defects.

This article evaluates reflectance confocal microscopy features of scalp melanoma but reports no new clinical results, suggesting further investigation is needed.

This study found that RCM combined with dermoscopy can differentiate disease states between alopecia areata, tinea capitis, nevus sebaceous, and linear scleroderma of the scalp by identifying distinct dermal and follicular patterns.

Reducing neutrophils or inhibiting NETs improves wound healing in sickle cell disease.

Stretching skin increases a certain protein that attracts stem cells, helping skin regeneration.

This study found that 60% of examined prostate tumors had new somatic substitutions in the SRD5A2 gene, affecting enzyme activity and potentially influencing prostate cancer progression.