Search
for
Sort by
Research
150-180 / 1000+ results
research PSS20 MEDIATION MODELING AND MEASUREMENT CHARACTERISTICS OF THE ITCH SEVERITY SCORE FROM A PHASE 2B TRIAL OF ORAL CP-690-550 IN PATIENTS WITH MODERATE TO-SEVERE PLAQUE PSORIASIS
This study found that the oral Janus kinase inhibitor CP-690,550 has a direct effect on reducing pruritus in patients with psoriasis, independent of clinician-assessed improvements in psoriasis severity.
research Gas-propelled anti-hair follicle aging microneedle patch for the treatment of androgenetic alopecia
This study developed a gas-propelled microneedle patch with puerarin/quercetin nanoparticles, which demonstrated improved hair-regenerating effects in an androgenetic alopecia mouse model by increasing drug delivery, alleviating oxidative stress, promoting angiogenesis, and rejuvenating senescent cells.
research Coenzyme Q10 phospholipidic vesicular formulations for treatment of androgenic alopecia: ex vivo permeation and clinical appraisal
This study found that Coenzyme Q10 delivered through transethosomes improved clinical outcomes for androgenic alopecia patients compared to CoQ10 solution.
research Using disease symptomatology to guide treatment in patients with central centrifugal cicatricial alopecia: introduction of C-CAT scoring tool
This study introduced the C-CAT, a new assessment tool for central centrifugal cicatricial alopecia, and found that established treatments improved symptoms in most patients over six months.
research Determination of 13 janus kinase inhibitors in anti-alopecia cosmetics by ultra-high performance liquid chromatography-tandem triple quadrupole composite linear ion trap mass spectrometry
This study developed a method using ultra-high performance liquid chromatography-mass spectrometry (UHPLC-MRM-IDA-EPI) for the rapid and sensitive detection of 13 JAK inhibitors in anti-alopecia cosmetics, showing excellent separation and accurate quantification with high recovery rates in tested matrices.
research Reporting Quality of Drug Safety Systematic Reviews: A Cross-Sectional Study
This study found that a medication error reporting system can significantly enhance patient safety through active participation of all stakeholders, with clinical pharmacists playing a crucial role in collaboration with other healthcare professionals.
research SnapshotDx Quiz: September 2018
This study of alopecia areata patients found that a 10 mg twice-daily dose of oral tofacitinib led to significant hair regrowth, suggesting it may be beneficial for treatment.
research ODAC Chairs Reveal Challenges, High Drama in a Decade of Service
This narrative review reflects on the challenges faced by FDA's Oncologic Drugs Advisory Committee members, highlighting public pressure, decision-making complexity, and the evolving landscape of cancer drug development.
research Integrated Safety Analysis of Ritlecitinib for the Treatment of Alopecia Areata (AA) From the Phase 2 and Phase 3 ALLEGRO Clinical Trial Program
In this study, ritlecitinib, an oral JAK3/TEC inhibitor, was evaluated for safety in patients aged 12 and older with alopecia areata across four clinical trials up to 36 months, showing a safety profile with reported adverse events and lab abnormalities summarized per dosing groups.
research Evaluation of the safety and effectiveness of intradermal administration of QR678 Neo® hair growth factor formulation: A phase‐IV, open‐label, single‐arm multi‐ethnicity clinical trial
This study found that intradermal administration of QR678 Neo® significantly reduced hair fall and improved hair growth in patients with androgenetic alopecia and female pattern hair loss, with no side effects reported during long-term follow-up.
research A hair growth questionnaire for use in the evaluation of therapeutic effects in men
This study developed a standardized questionnaire to measure patient-perceived changes in hair growth and appearance, which showed significant favoring of active treatment over placebo in a clinical trial for male androgenetic alopecia.
research Development of squamous cell carcinoma from erythroplasia of Queyrat following photodynamic therapy
Photodynamic therapy may not work for erythroplasia of Queyrat and could lead to invasive squamous cell carcinoma.
research Fractional ablative CO2 laser and oral isotretinoin—A prospective randomized controlled split‐face trial comparing concurrent versus delayed laser treatment for acne scars
This study observed that treating acne scars with fractional ablative laser concurrently with isotretinoin improved outcomes more effectively compared to applying the laser 6 months after isotretinoin treatment ended, as measured by the Quantitative Global Acne Scarring Grading System.
research The Polycystic Ovary Syndrome Health-Related Quality-of-Life Questionnaire: Confirmatory Factor Analysis
This study found that the revised 43-item PCOSQ had better validity and reliability than the original version, although further studies are needed to assess its predictive efficacy.
research Multifunctional Hydrogel with Dual Functions of ROS Scavenging and Responsive Antibiotic Release for Synergistic Oral Mucositis Treatment
This study developed a multifunctional hydrogel, QTMP-Gel, which significantly accelerated wound healing in an oral mucositis hamster model by providing antioxidant and antibacterial effects, reducing inflammation, and controlling infection.
research BIO-ANALYTICAL METHOD DEVELOPMENT AND VALIDATION OF FINASTERIDE, TADALAFIL, AND ITS APPLICATION TO PHARMACOKINETIC STUDIES IN RAT PLASMA BY USING LC-MS/MS
This study describes a new LC-MS/MS method for analyzing Finasteride and Tadalafil, demonstrating system suitability, linearity, and accuracy in pharmacokinetic studies in rats, aligning with USFDA guidelines.
research Les droits des étrangers et leur sauvegarde dans ll'ordre communautaire.
In this study, phospholipid-polymer hybrid nanoparticles were found to enhance quercetin's hair regrowth potential in testosterone-induced alopecia in rats by efficiently delivering the compound to hair follicles.
research INIBIDORES DA JANUS QUINASE PARA O TRATAMENTO DA ALOPECIA AREATA
This review assessed randomised clinical trials on the efficacy and safety of topical and systemic JAK inhibitors for alopecia areata, finding significant hair coverage improvement with ritlecitinibe and baricitinibe, though prolonged treatment is often needed to maintain results.
research Development of Chinese Version of Polycystic Ovary Syndrome Health-Related Quality of Life Questionnaire (Chi-PCOSQ)
This study developed the Chi-PCOSQ, a culturally adapted Chinese assessment tool for measuring health-related quality of life in women with polycystic ovary syndrome, showing promising reliability and validity.
research Cyproterone Acetate Quantification in Human Plasma by High-performance Liquid Chromatography Coupled to Atmospheric Pressure Photoionization Tandem Mass Spectrometry
This study developed a sensitive HPLC-MS/MS method for determining cyproterone acetate levels in human plasma and found no significant difference in its concentration between two oral formulations in bioequivalence testing.
research Ultra-Performance Liquid Chromatography with Electrospray Ionization Tandem Mass Spectrometry for the Determination of Ketoconazole in Anti-Dandruff Shampoo
This study developed a fast and sensitive ultra-high performance liquid chromatography method to quantify ketoconazole in antidandruff emulsions, showing comparable results to labeled concentrations.
research Proceedings of the International Conference on Translational and Integrative Medicine
This study evaluated the antimicrobial activity of a newly synthesized fluoroquinolone against Staphylococcus, Streptococcus, and Escherichia coli strains. The researchers compared results from the microdilution technique and agar disk diffusion method to EUCAST's recommended breakpoint values, building on promising in silico molecular docking tests.
research Materials, Syntheses and Biomedical Applications of Nano-Quercetin Formulations: A Comprehensive Literature Review
This review explores nano-quercetin formulations to enhance the solubility, stability, and targeted delivery of quercetin, highlighting its potential efficacy in treating cancer, inflammation, metabolic diseases, and tissue regeneration, though challenges in biocompatibility, toxicity, and production remain, per this source.
research Measuring the impact on quality of life of infants with atopic dermatitis in a dedicated clinic
Atopic dermatitis significantly lowers the quality of life for infants and their families.
research Effects of Tianqi trichogen on the hair growth of animals
This study found that Tianqi trichogen promoted hair growth in tested animals, with no observed photoallergic reactions or significant skin allergies.
research Implementation of the JCCP Premises Standards for cosmetic interventions
This article discusses the JCCP's new Premises Standards for aesthetic practitioners, focusing on how these guidelines help ensure patient safety, and reports no new research findings.
research Qu-Shi-Yu-Fa Decoction Promotes Hair Cycle and Keratinization by Upregulating Foxn1 and Tgm3 to Treat Androgenetic Alopecia
In a study using an androgenetic alopecia mouse model, researchers found that Qu-shi-yu-fa Decoction significantly promoted hair regeneration by enhancing follicle transition and activating key pathways, with potential therapeutic targets such as FOXN1 and TGM3 identified.
research Associated Factors of Quality of Life in Adult Female Acne Coexisting with Hyperandrogenism and Polycystic Ovarian Syndrome using the Dermatology Life Quality Index
This study found that acne in adult females, especially when moderate to severe or associated with certain aggravating factors, significantly affected quality of life, particularly in terms of self-consciousness and daily activities.
research 598 Response to ritlecitinib treatment based on salt improvement scores in patients with alopecia areata (AA): Post hoc analysis of the allegro phase 2b/3 study
This study found that treatment with ritlecitinib led to significant scalp hair regrowth in patients with alopecia areata at Weeks 24 and 48, with higher response rates observed in those receiving 50 mg compared to 30 mg doses.