The Rights of Foreigners and Their Protection in the Community Order
January 1995
in “
Cahiers de droit européen
”
TLDR Phospholipid-polymer hybrid nanoparticles could help treat hair loss by delivering quercetin effectively.
The study aimed to deliver quercetin to hair follicles using DPPC-PLGA hybrid nanoparticles for treating alopecia. The nanoparticles were characterized and tested on rat models with testosterone-induced alopecia. Key findings included a mean vesicle size of 339 nm, a zeta potential of -32.6 mV, and an entrapment efficiency of 78%. The drug release after 12 hours was 47.27%. The study found that the nanoparticles were effectively taken up by hair follicles and improved hair regrowth by inhibiting hair follicle cell apoptosis. The conclusion was that phospholipid-polymer hybrid nanoparticles could be a promising delivery system for quercetin in managing androgenic alopecia.