Using Disease Symptomatology to Guide Treatment in Patients With Central Centrifugal Cicatricial Alopecia: Introduction of C-CAT Scoring Tool
September 2024
Studysummary This study introduced the C-CAT, a new assessment tool for central centrifugal cicatricial alopecia, and found that established treatments improved symptoms in most patients over six months.
Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer
This study introduces the CCCA Clinical Assessment Tool (C-CAT), a new scale designed to quantify symptom severity in patients with central centrifugal cicatricial alopecia (CCCA) to guide treatment and track disease progression. In a retrospective review of 82 patients over at least six months, the average initial C-CAT score indicated mild to moderate disease activity. After treatment, 88% of patients showed improvement, with 48% achieving remission. Common treatments included intralesional kenalog injections and topical clobetasol, with patients needing an average of 3.6 different treatments for a therapeutic response. The C-CAT provides a structured method to assess CCCA severity, promoting personalized treatment and aiding in understanding disease progress, despite potential inter-rater variability due to subjective components.
