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This study found that liposomal formulations improved minoxidil delivery to skin layers compared to niosomes and a control solution, suggesting enhanced potential for topical hair loss treatment.

This study found that drug delivery through human scalp skin may be more effective for lipophilic and hydrophilic drugs compared to abdominal skin, highlighting the potential of intrafollicular delivery methods.

This study suggests that minoxidil activates PGHS-1, which may explain its hair growth-stimulating effects and could aid in designing more potent hair growth-promoting drugs.

This study found that hair depigmentation in mice and humans can be a dynamic indicator of KIT inhibition by the drug SU11248, correlating with treatment periods.

This review discusses newly identified non-Edg family lysophosphatidic acid receptors, detailing their roles in vascular development, platelet activation, and hair growth, and reports no clinical results.

This study found that minoxidil is bioactivated through sulfation by the phenol-sulfating form of phenol sulfotransferase in human liver.

This article reviews historical and recent developments related to toxic shock syndrome (TSS), emphasizing the increase in cases among young women using tampons, and calls for new research tools but does not report new results.

This study identified a sulfotransferase activity in rat liver that catalyzes the sulfation of minoxidil, contributing to its delayed hypotensive effects.

This study found that prostaglandin metabolism enzymes are present in human hair follicles, suggesting a potential role in hair growth and differentiation, with some expression differences between men and women.

This study found that disrupting inflammasome signaling by eliminating caspase-1 and -11 in mice reduced skin inflammation and delayed the onset of disease, highlighting their role in skin disease pathogenesis.

This study found that at least four different human sulfotransferase activities contribute to the sulfation of minoxidil, complicating predictions of individual responses based on ST levels.

Minoxidil, propranolol, and furosemide effectively control severe hypertension, but may cause sodium retention.

In this study, jaw wiring led to significant weight loss in patients with severe obesity, but two-thirds regained weight after the wires were removed.

In this study, male rats exposed in utero to low-dose chemical mixtures had permanent reproductive tract alterations, suggesting additive effects even at doses below individual adverse levels.

Minoxidil not effective in preventing chemotherapy-induced hair loss.

This study found that minoxidil-loaded niosomes with a Span 60 and cholesterol ratio of 1:2 significantly increased skin retention of minoxidil compared to control gel.

The study explains how minoxidil sulfate causes vasodilation in rabbits by opening potassium channels and inhibiting calcium channels.

Nitrendipine and nifedipine effectively block muscle contractions, while papaverine relaxes them and minoxidil needs high amounts to work.

Hair treatments like bleaching increase friction by exposing tiny pores on the hair surface.

This study found that combining minoxidil with all-trans retinoic acid additively promoted hair growth in vitro by activating certain cell survival pathways and reducing apoptosis markers more effectively than minoxidil alone.

In this study, glyburide prevented or significantly reduced cardiovascular lesions in dogs caused by minoxidil by blocking its hemodynamic effects, suggesting the toxicity is related to these profound effects rather than direct heart toxicity.

In this animal study, researchers found that cedrol, a constituent from Platycladus orientalis, significantly promoted hair growth in a dose-dependent manner in female C57BL/6 mice, surpassing results from blank control and 2% minoxidil groups over 21 days.

Human platelets change minoxidil to minoxidil sulfate, helping blood vessels widen.

This study discusses levetiracetam's role as an alternative treatment for idiopathic generalized epilepsies, highlighting its potential effectiveness, especially for patients unsuitable for valproate.

This study found that overexpressing PLC5 in Arabidopsis thaliana reduced root growth but improved drought tolerance, and suggests PIP2 is crucial for root hair growth.

This study demonstrates that exfoliative cutaneous lupus erythematosus in German short-haired pointers involves a cellular and humoral immune response against the epidermal basement membrane, with poor response to immunosuppressive therapy.

Minoxidil affects collagen-related genes, potentially helping treat fibrosis.

This paper describes recent advancements in the synthesis of thiasteroids but reports no new experimental results, noting that introducing heteroatoms in steroidal structures has potential biological effects.

Toxic shock syndrome is caused by a complex interaction of bacterial toxins and the immune system, and understanding this can help improve diagnosis and treatment.

This study found that the 11R-No. 10 peptide, delivered transdermally, significantly inhibited melanogenesis and produced a whitening effect in a UV-induced sun-tanning guinea pig model without cytotoxicity.