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Genetic mutations cause various hair diseases, and whole genome sequencing may reveal more about these conditions.

Antiandrogens like flutamide are effective in treating conditions like prostate cancer and hair loss, but there's a need for more potent versions. Understanding their structure can help develop better treatments.

Apple polyphenol, especially oligomeric procyanidins, can reduce fat absorption and lower blood fat levels.

Research on epidermal stem cells has advanced significantly, showing promise for improved clinical therapies.

Antiandrogens are effective for conditions like prostate cancer and skin issues, but more research is needed to confirm their benefits and minimize side effects.

NcoA4 may have roles beyond helping control gene activity, possibly affecting cell behavior and stability.

Spironolactone works well for acne and hirsutism, isotretinoin is very effective for acne and may have antiandrogenic effects, and 5 alpha-reductase inhibitors should be considered antiandrogens.

The ketogenic diet can worsen biotin deficiency, suggesting a need for biotin supplements.

Different drugs can treat high male hormone levels in women, but they have various effects and some may harm a fetus.

Choline and biotin are important for liver health and preventing certain deficiencies in animals, and more research is needed to understand their benefits in humans.

The document suggests creating a secure database for indigenous knowledge and recommends that the TKDL actively fight patents that slightly alter traditional knowledge.

Good nutrition is crucial for health and preventing disease, and supplements can help prevent nutrient deficiencies.

Hair straightening changes hair structure and can cause damage if done wrong, but improvements in the methods are expected to continue.

Hair straightening methods have advanced to improve effectiveness and reduce damage, but still rely on heat and chemicals.

Enzymatically extracted bear oil has more unsaturated fats and significantly increases hair growth in mice.

Androgens are important for female fertility and could help in IVF treatment, but also play a role in causing PCOS.

Melanoma's complexity requires personalized treatments due to key genetic mutations and tumor-initiating cells.

The conclusion is that obesity should be managed with a slow, balanced approach to diet and exercise, with medication and surgery as additional options, and education and access to care are important.

Lotion with fucoidan from brown seaweed improved skin and reduced allergy symptoms in mice with dermatitis.

Mutations in the KRT85 gene cause hair and nail problems.

Adding fetal calf serum helps Merkel cells survive and change shape.

Adding fetal calf serum to the medium kept Merkel cells alive and changed their shape.

Removing an adrenal tumor can significantly reduce high androgen levels in postmenopausal women.

Compounds from Jatropha cordata bark have significant anti-inflammatory effects and could help with hair loss.

A 13-year-old girl's masculine symptoms improved after surgery for a rare adrenal tumor that produced male hormones.

Flutamide effectively reduced excessive hair growth and improved related symptoms in hirsutism patients without significant side effects.

Flutamide, an antiandrogen, has minimal impact on female rat endocrine systems and does not significantly change their reproductive cycles.

A new microneedle patch and yellow light therapy significantly promote hair regrowth.

Pure carbon nanotubes are safe for mice, but impure ones cause immune issues and hair loss.

The industry should promote pure luxury hair fibers, improve technology, and diversify products to support growers and ensure sustainable use.