2 citations
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October 2021 in “Egyptian Journal of Chemistry” In this study, researchers used pumpkin aqueous extract to create iron nanoparticles, finding them effective at inhibiting harmful bacteria found in burn and wound infections, as well as promoting burn healing and hair growth in a laboratory mouse model.
July 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study reports that a newly formulated herbal hair oil may be a stable and safe option to promote hair growth and reduce hair fall without toxic chemicals.
July 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This research formulated a herbal hair oil using ingredients like pumpkin seed, bhringraj, and amla to reduce DHT levels and stimulate hair growth, with findings suggesting that the product is stable, suitable for the scalp, and free from toxic chemicals.
12 citations
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January 2018 in “Pharmacology & pharmacy” This study found that components derived from Uromedic® pumpkin seeds, especially Δ7-sterols, may inhibit DHT production and AR binding, potentially benefiting prostate and bladder health by moderating these mechanisms.
February 2025 in “Clinical & Experimental Dermatology and Therapies” In this randomized trial, oral supplementation with Serenoa repens, pumpkin seed extracts, and cysteine significantly improved the clinical effectiveness of topical 5% minoxidil lotion for treating androgenic alopecia in men and women compared to minoxidil alone, with both treatments being well tolerated.
December 2025 in “JURNAL PIJAR MIPA” This study found that a natural hair tonic spray formulated from 15% water pumpkin fruit extract promoted rabbit hair growth to a degree comparable to a synthetic control.
January 2025 in “Nanotechnology Reviews” This study reported a green synthesis method for copper oxide nanoparticles using pumpkin seed extract, achieving significant antibacterial activity against Bacillus subtilis and moderate cytotoxic effects against certain cancer cell lines, indicating potential biomedical applications for these eco-friendly nanomaterials.
4 citations
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October 2025 in “Molecules” This study concluded that extracts from fermented pumpkin peel and pulp, processed with Lactobacillus strains and kombucha, may serve as multifunctional cosmetic ingredients, offering antioxidant protection, anti-aging, and skin regeneration benefits by demonstrating cytoprotective effects and reducing inflammatory cytokines in cell assays.
January 2017 in “Archives of Aesthetic Plastic Surgery” This study reported that using a shampoo and tonic containing horse placental growth factor improved hair thickness and density in postpartum women over three months.
40 citations
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August 2018 in “Skin appendage disorders” This review examines complementary and alternative medicine for alopecia and finds limited support from robust clinical trials, highlighting the need for standardized studies to evaluate efficacy and safety.
2 citations
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January 2022 in “Dermatologic Therapy” Natural products like saw palmetto, caffeine, melatonin, marine extracts, rosemary oil, procyanidin, pumpkin seed oil, and cannabidiol oil could potentially treat male hair loss.
January 2026 in “Frontiers in Nutrition” This study found that various dietary supplements positively impacted hair density and were well-tolerated among patients with androgenetic alopecia, suggesting they may be useful adjuncts or alternatives to standard treatments.
January 2025 in “International Journal of Trichology” This review highlighted the hype surrounding topical hair growth ingredients such as Redensyl, Procapil, and others, noting promising results but also emphasizing the limitations of existing studies, including small sample sizes and lack of standard therapy comparisons.
This study found that the nutraceutical product DERM decreased the pro-inflammatory cytokine IL-6 in mesenchymal stem cells under in vitro conditions.
This study reviews the use of natural products, like herbal extracts and essential oils, in treating male pattern baldness, noting their potential benefits compared to conventional therapies that may carry side effects or ethical concerns.
December 2023 in “Bulletin of Pharmaceutical Sciences Assiut” In this study, GC/MS analysis revealed variability in the quality of Syrian herbal formulations for BPH, with variations in tocopherol content, presence of parabens, and shortages of certain phytosterols.
67 citations
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February 2015 in “Life Sciences” This review discusses phytotherapy options for managing benign prostatic hyperplasia, noting some herbal agents show promise in trials for mild-moderate symptoms but more evidence is needed for others.
10 citations
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June 2019 in “International Journal of Cosmetic Science” This review discusses the potential benefits of phytochemicals for hair care and emphasizes the need for more robust preclinical and clinical studies, without reporting new clinical results.
1 citations
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June 2014 in “Vìsnik farmacìï” This study developed an emulsion formulation with optimal properties for androgenetic alopecia treatment using saw palmetto and Japanese Sophora extracts, evaluated for stability and release of active ingredients.
December 2025 in “Brazilian Journal of Hair Health” This review highlights that natural DHT blockers like saw palmetto and pumpkin seed oil show promise in managing androgenetic alopecia, though clinical data varies, and further research is needed to confirm their efficacy and safety in comparison to conventional pharmaceuticals.
February 2024 in “International journal of biology, pharmacy and allied sciences” This review discusses the potential of plant-based preparations for treating hair loss and reports no new clinical results; the authors highlight herbs with evidence of efficacy against alopecia.
6 citations
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April 2025 in “Frontiers in Sustainable Food Systems” This review highlights the potential of valorizing vegetable waste by extracting valuable biomolecules for use in food, nutraceuticals, and energy, noting that while promising methods exist, several niche areas lack sufficient research on a global scale.
January 2019 in “International Journal of Herbal Medicine” This study concluded that a hair emulgel formulation combining extracts from four medicinal plants demonstrated desirable characteristics of spreadability, viscosity, pH, and safety, making it effective, harmless, and economical for potential hair care use.
54 citations
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May 2017 in “Biomedicine & Pharmacotherapy” This review discusses the nutrient profile and potential health benefits of pumpkin and watermelon seeds, concluding they are underutilized and could be developed into various nutraceuticals.
54 citations
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September 2002 in “Annals of Pharmacotherapy” This review discusses various herbal therapies, such as Serenoa repens and Pygeum africanum, for treating benign prostatic hyperplasia, noting their potential but highlighting unresolved questions about their efficacy and safety.
1 citations
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August 2025 in “Seeds” This review examines the potential of Cucurbitaceae seeds, such as those from watermelon, melon, and pumpkin, as sustainable and innovative ingredients in cosmetics, highlighting their rich bioactive composition and benefits for skin and hair, despite challenges like environmental instability and low permeability.
This study concluded that phytotherapy offers a potentially effective and safer alternative to conventional treatments for androgenetic alopecia by reducing hair loss progression without the usual adverse effects.
November 2024 in “SKIN The Journal of Cutaneous Medicine” This case series suggests that a nutraceutical gummy may effectively promote hair regrowth and reduce hair shedding in women with female pattern hair loss and telogen effluvium.
15 citations
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June 2018 in “Food Reviews International” This review discusses the potential benefits of pumpkin seed oil for men's health, particularly in conditions such as benign prostatic hyperplasia, overactive bladder, and androgenic alopecia, but reports no new clinical results.
4 citations
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February 2021 in “Journal of Cosmetic Dermatology” This study found that pumpkin seed oil significantly improved hair parameters in females with pattern hair loss, demonstrating potential as a treatment comparable to minoxidil 5% foam.