research Aberrant Inflammasome Activation as a Driving Force of Human Autoimmune Skin Disease
Faulty inflammasome activation may lead to autoimmune skin diseases and could be a target for new treatments.
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research Janus Kinase Inhibitors in Dermatology: A Systematic Review
JAK inhibitors help with skin conditions but need more research on dosing and safety.
research The Influence of Interferon on Healthy and Diseased Skin
Type I interferons play a key role in the development of various skin diseases.
research Use of Complementary Alternative Medicine and Supplementation for Skin Disease
Some alternative medicine treatments might work for skin conditions, but their effectiveness and safety differ a lot.
research Novel Advances of Histone Modification in Inflammatory Skin Diseases and Related Treatment Methods
Histone modification is key in treating chronic inflammatory skin diseases.
research Suprabasal Desmoglein 3 Expression in the Epidermis of Transgenic Mice Results in Hyperproliferation and Abnormal Differentiation
Overexpressing Dsg3 in mice skin causes excessive cell growth and abnormal skin development.
research The C3H/HeJ Mouse and DEBR Rat Models for Alopecia Areata: Review of Preclinical Drug Screening Approaches and Results
Both mouse and rat models are effective for testing alopecia areata treatments.
research Cell Death as an Architect of Adult Skin Stem Cell Niches
Cell death shapes skin stem cell environments, affecting inflammation, repair, and cancer.
research Type 1 Interferon Signature in the Scalp Lesions of Alopecia Areata
Alopecia areata shows a unique type 1 interferon signature, suggesting potential treatment by targeting this pathway.
research The Treatment of Alopecia Areata
Different treatments for alopecia areata have unpredictable results and varying success rates.
research Comparative Efficacy and Adverse Clinical Events of Methotrexate Versus Azathioprine with Steroid Mini Pulse Therapy in the Management of Moderate to Severe Alopecia Areata: A Tertiary Centre Based Interventional Study
Methotrexate with steroids is slightly more effective than azathioprine with steroids for treating severe alopecia areata.
research Cutaneous Lupus Erythematosus: A Comprehensive Review
The document concludes that skin biopsies, genetic and environmental factors, and specific treatments are important in managing cutaneous lupus erythematosus.
research Androgen Effects in Mammals
Testosterone is crucial for development, growth, and various body functions in mammals.
research Structural Changes in Human Skin After Topical Application of Glucocorticoids Assessed by In Vivo Imaging Technologies
Topical glucocorticoids thin the skin and change collagen structure.
research The IL-23/IL-17 Pathway in Inflammatory Skin Diseases: From Bench to Bedside
Targeting the IL-23/IL-17 pathway effectively treats several inflammatory skin diseases.
research Zinc Therapy in Dermatology: A Review
Zinc is effective for treating various skin conditions, including warts and acne.
research Cutaneous Toxicities of New Treatments for Melanoma
New melanoma treatments can cause skin side effects, including skin cancer and rashes, but combining treatments may reduce these risks.
research Effect of Cyclosporin on Hair-Existing Area of Nude Mice
Cyclosporin extends hair growth in mice, but high-dose corticosteroids block this effect.
research The Role of Mesenchymal Stem Cell-Derived Exosomes in Skin Regeneration, Tissue Repair, and the Regulation of Hair Follicle Growth
research Psoriasiform Skin Reaction Due to Brazilian Keratin Treatment
Brazilian Keratin Treatment can cause skin reactions like redness and scaling, possibly due to formaldehyde.
research Autophagy Critically Controls Skin Inflammation and Apoptosis-Induced Stem Cell Activation
Autophagy helps control skin inflammation and cancer responses and regulates hair growth by affecting stem cell activity.
research Triton Modified Polyethyleneimine Conjugates Assembled With Growth Arrest-Specific Protein 6 for Androgenetic Alopecia Transdermal Gene Therapy
The treatment effectively promotes hair regrowth in androgenetic alopecia without causing skin irritation.
research Expression and Function of Group IIE Phospholipase A2 in Mouse Skin
sPLA2-IIE is crucial for normal hair follicle structure and skin health.
research Combination Therapy With Oral PUVA and Corticosteroid for Recalcitrant Alopecia Areata
The combination of oral PUVA and corticosteroids helps regrow hair in severe alopecia areata.
research Controlled Delivery of T-box21 Small Interfering RNA Ameliorates Autoimmune Alopecia in a C3H/HeJ Mouse Model
Controlled delivery of specific RNA and IL-4 restored hair growth in mice with autoimmune alopecia.
research Disturbance of Immune Microenvironment in Androgenetic Alopecia Through Spatial Transcriptomics
Androgenetic alopecia involves immune cell disruptions, especially increased CD4+ T cells around hair follicles.
research Exosomes In Dermatological Research: Unveiling Their Multifaceted Role In Cellular Communication, Healing, And Disease Modulation
Exosomes could help treat skin and hair issues by improving healing and reducing stress.
research Advances and Challenges in the Treatment of Skin Diseases with the Transdermal Drug Delivery System
New skin disease treatments using TDDS are improving but face challenges like side effects and high costs.
research Astilbin Activates the Reactive Oxidative Species/PPARγ Pathway to Suppress Effector CD4+ T Cell Activities via Direct Binding With Cytochrome P450 1B1
Astilbin can potentially calm overactive immune responses, like in Type 1 Diabetes, by suppressing certain cell activities and reducing inflammation.
research Alopecia Areata Is Driven by Cytotoxic T Lymphocytes and Is Reversed by JAK Inhibition
Alopecia areata can be reversed by JAK inhibitors, promoting hair regrowth.