research Enhancing 1α-Hydroxylase Activity with the 25-Hydroxyvitamin D-1α-Hydroxylase Gene in Cultured Human Keratinocytes and Mouse Skin
Adding a specific gene to skin cells can help treat skin disorders like psoriasis.
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research Under Development JAK Inhibitors for Dermatologic Diseases
New JAK inhibitor drugs show promise for treating skin diseases but need more research on safety and effectiveness.
research Potential Medical Uses of Cannabigerol: A Brief Overview
CBG may help with various medical conditions but needs more human research to confirm safety and effectiveness.
research Topical Tacalcitol Ointment Can Be a Good Therapeutic Choice in Erythromelanosis Follicularis Faciei et Colli
Topical tacalcitol ointment can help improve symptoms of EFFC.
research Various Applications of Tofacitinib and Ruxolitinib in Dermatology and Rheumatology: A Review of Current Evidence and Future Perspective
Tofacitinib and ruxolitinib are effective and safe for treating various autoimmune skin and joint disorders.
research Use of Complementary Alternative Medicine and Supplementation for Skin Disease
Some alternative medicine treatments might work for skin conditions, but their effectiveness and safety differ a lot.
research Novel Drugs Targeting Retinoic Acid Receptors
Newer retinoid drugs are effective for skin conditions but have significant side effects.
research Mechanisms Regulating Skin Immunity and Inflammation
The document concludes that understanding how the skin's immune system and inflammation work is complex and requires more research to improve treatments for skin diseases.
research Alopecia Areata Profiling Shows TH1, TH2, and IL-23 Cytokine Activation Without Parallel TH17/TH22 Skewing
Alopecia areata involves immune activation in the scalp, suggesting treatments targeting TH1, TH2, and IL-23 pathways.
research Human αβ and γδ T Cells in Skin Immunity and Disease
Certain types of T cells are essential for healthy skin and play a role in skin diseases, but more research is needed to improve treatments.
research Understanding Autoimmunity of Vitiligo and Alopecia Areata
Both vitiligo and alopecia areata involve an immune response triggered by stress and specific genes, with treatments targeting this pathway showing potential.
research Local Heroes or Villains: Tissue-Resident Memory T Cells in Human Health and Disease
Tissue-resident memory T cells can protect against infections and cancer but may also contribute to autoimmune diseases.
research Metabolic Syndrome and the Skin: A More Than Superficial Association
Some skin conditions may indicate metabolic syndrome, which could help with early detection and management of related health issues.
research Oral Retinoids in Dermatology
Oral retinoids are effective for severe skin conditions but require careful use due to side effects.
research Does Prolactin Play a Role in Skin Biology and Pathology?
Prolactin may be important for skin growth and immune function.
research Cutaneous Manifestations of Anabolic-Androgenic Steroid Use in Athletes
Using anabolic-androgenic steroids can cause skin problems like acne and hair loss in athletes.
research Harnessing Neuroendocrine Controls of Keratin Expression: A New Therapeutic Strategy for Skin Diseases?
Using neurohormones to control keratin can lead to new skin disease treatments.
research Group IID, IIE, IIF, and III Secreted Phospholipase A2s
Different sPLA2 enzymes affect immunity, skin and hair health, reproduction, and may be potential targets for therapy.
research Cyclosporine Therapy for Bullous Erythema Multiforme
Cyclosporine cleared a woman's resistant skin condition quickly and kept it away for over a year.
research Can Dermal Delivery of Therapeutics Be Improved Using Thermoresponsive Nanogels?
Thermoresponsive nanogels show promise for delivering medicine through the skin but need more safety testing and regulatory approval before clinical use.
research Role of Liposomal Drug-Delivery System in Cosmetics
Liposomes improve the delivery and effectiveness of cosmetic ingredients but face challenges like cost and stability.
research Vitamin D3 and Chemotherapy-Induced Alopecia
Vitamin D3 may prevent hair loss from chemotherapy, but side effects and cancer cell protection are concerns.
research Anticytokine Therapy, Particularly Anti-IFN-γ, in Th1-Mediated Autoimmune Diseases
Blocking interferon-gamma might help treat various autoimmune diseases.
research Metabolism and Skin Diseases
Skin health and diseases are closely linked to metabolic processes.
research The Role of Cytochrome P-450 in Dermatology
Cytochrome P-450 enzymes in the skin help break down various substances and could be targeted to treat skin conditions.
research Oral Lichen Planus: A Chronic Systemic Disease with Immune-Mediated Pathogenesis
Oral lichen planus is a chronic disease causing mouth discomfort and sometimes needs immunosuppressive treatment.
research In Vivo Microautoradiography of [3H]1,24(OH)2D3 (Tacalcitol) Following Topical Application to Normal Rats and In Vitro Metabolism in Human Keratinocytes
Topical tacalcitol can treat psoriasis by acting directly on skin cells.
research Recent Insight on the Management of Lupus Erythematosus Alopecia
Early treatment of Lupus Erythematosus Alopecia can prevent permanent hair loss, and various medications are effective.
research Unlocking the Power of Light on the Skin: A Comprehensive Review on Photobiomodulation
Light-based treatment, Photobiomodulation, shows promise for non-invasive skin therapy with few side effects.
research An Overview of Scalp Dermatoses in a Tertiary Care Institute
Scalp skin conditions are more common in young adults and teenagers, especially males, with itching being the main complaint. The most common conditions are psoriasis and alopecia areata, and these can significantly affect a person's social life due to their psychological impact.