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Mutations in the SRD5A3 gene cause a new type of glycosylation disorder by blocking the production of a molecule necessary for protein glycosylation.

Finasteride doesn't effectively treat hair loss in postmenopausal women.

Blocking the enzyme 5α-reductase can shrink the prostate and help treat enlarged prostate issues.

Creating stronger blockers for skin enzymes might lead to better treatment for conditions like acne and excessive hair growth.

AGA causes hair loss by shrinking hair follicles due to DHT binding, and can be treated with finasteride and minoxidil.

Hair loss in women is genetic, diagnosed by examination and biopsy, and treated with minoxidil, finasteride, or transplantation.

Some patients taking finasteride or dutasteride may have ongoing sexual problems and depression even after stopping the medication.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Finasteride effectively treats BPH, but needs more trials to understand potential.

Early diagnosis and treatment, using finasteride, minoxidil, or hair transplantation, improves hair loss outcomes.

Sebocytes play a key role in controlling androgen levels in human skin.

Different animals have unique versions of the enzyme that changes testosterone into another hormone, which is important for creating effective treatments for prostate and hair loss conditions.

Finasteride effectively treats frontal hair loss with few side effects.

Finasteride treats enlarged prostate and may help with baldness, but effects on sexual function and male fetuses are unclear.

Minoxidil, finasteride, and low-level laser light therapy effectively treat hair loss.

Hair loss needs more research for better treatments.

Oestrogens are key for bone growth during puberty in both boys and girls.

A substance called DKK-1 increases in balding areas and causes hair cells to die when exposed to DHT.

Male hormones, particularly DHT, are linked to male pattern hair loss, and treatments like finasteride can help, but they don't work for postmenopausal women's hair loss, which may have different causes.

Congenital Adrenal Hyperplasia is a genetic disorder with two forms, causing symptoms like early puberty and severe acne, but can be identified through screening and treated with glucocorticoids.

Antiandrogens are somewhat effective in reducing excessive hair growth in women.

Finasteride safely lowers DHT levels without affecting testosterone.

Too much androgen can cause hair loss; finasteride may help.

Androgens, like testosterone, are crucial for early testicular descent in rats.

PRP treatment improves hair growth, and the device used can affect results, with some being more effective.

Inflammation may be linked to hair loss, and targeting specific enzymes could help treat it.

Finasteride effectively treats baldness but may cause sexual side effects.

Testosterone's muscle-building effects do not require its conversion to DHT.

Finasteride effectively inhibits 5α reductase, while plant extracts like Permixon and Bazoton don't show significant results.

Finasteride exposure in pregnancy causes genital abnormalities in male rats.