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JAK inhibitors show promise for treating various skin diseases.

Janus kinase inhibitors show promise in treating alopecia areata but need better topical formulations.

XMU-MP-1 stops cell growth in a human mini-organ and reduces the effectiveness of the chemotherapy drug paclitaxel.

Researchers found genetic mutations causing hypohidrotic ectodermal dysplasia in 88% of studied patients and identified new mutations and genetic variations affecting the disease.

Hair loss in Androgenetic alopecia (AGA) is due to altered cell sensitivity to hormones, not increased hormone levels. Hair growth periods shorten over time, causing hair to become thinner and shorter. This is linked to miscommunication between cell pathways in hair follicles. There's also a change in gene expression related to blood vessels and cell growth in balding hair follicles. The exact molecular causes of AGA are still unclear.

Aging causes hair to gray and thin, with the timing of graying varying by race, and factors like oxidative stress and genetics can lead to hair loss.

Hair follicle stem cells are important for maintaining healthy skin and interact with many signals.

The Wnt signaling pathway is not a major factor in the development of keratoacanthoma, a type of skin tumor.

Insulin resistance is a key factor in polycystic ovary syndrome, but genetics may also contribute.

Minoxidil improves blood flow and vessel flexibility, potentially helping with vascular stiffness.

The research found that a complex gene network, controlled by microRNAs, is important for hair growth in cashmere goats.

Polycystic Ovary Syndrome (PCOS) is a hormonal disorder in women that can cause infertility and other health issues, and it may be improved by treatments that increase insulin sensitivity.

The gene Prss53 affects hair shape and bone development in rabbits.

Acne patients have higher levels of mTOR in their skin, which could be linked to future metabolic disease.

Researchers found genes linked to feather growth speed in Shouguang chickens, highlighting two genes that might explain differences in feathering.

Blocking miR-27a increases sheep hair follicle stem cell growth and decreases cell death, which could help improve wool quality and treat hair loss.

RE-ORGA, a Korean herb extract, may help prevent hair loss.

A new carrier improves skin delivery of tofacitinib for treating inflammatory skin diseases.

Different people show different symptoms for genetic diseases because of how sensitive their bodies are to small changes in important factors.

XEDAR triggers a specific signaling pathway in cells.

Dihydrotestosterone causes p27 protein breakdown in ovarian and breast cancer cells by binding with SKP2.

Baicalin may help treat hair loss by promoting hair follicle growth and activating specific cellular pathways.

An enzyme other than TNAP might be responsible for vitamin B-6 metabolism in the skin.

Mice can regenerate ear tissue without the p53 protein.

3-Deoxysappanchalcone helps human hair cells grow and stimulates hair growth in mice by affecting certain cell signaling pathways.

Glycyrrhizic acid and licorice extract can significantly reduce unwanted hair growth.

Non-immune factors play a significant role in alopecia areata.

Gynostemma pentaphyllum and its component damulin B could help hair grow by activating certain cell pathways.

The Wnt/β-catenin pathway is important for body functions and diseases, and targeting it may treat conditions like cancer, but with safety challenges.

Damaging mutations in NFKB2 cause a severe and distinct form of primary immunodeficiency with early-onset and often ACTH-deficiency.