6 citations,
September 2022 in “Frontiers in pharmacology” Epimedium extract helps increase skin pigmentation and could be a new treatment for conditions with reduced pigmentation.
4 citations,
November 2017 in “Scientific Reports” The research provides a gene-based framework for hair biology, highlighting the Hippo pathway's importance and suggesting links between hair disorders, cancer pathways, and the immune system.
42 citations,
February 2014 in “Stem Cells and Development” Vitamin C helps adipose-derived stem cells grow and may support hair growth.
June 2023 in “Current Issues in Molecular Biology” DN106212, an extract from a plant, is better at promoting hair growth than other tested substances by affecting hair growth factors and follicle development.
105 citations,
August 2010 in “Pharmacology & therapeutics” Formyl-peptide receptor agonists could be new anti-inflammatory drugs.
3 citations,
June 2017 in “Methods” Researchers created a model to understand heart aging, highlighting the role of microRNAs and identifying key genes and pathways involved.
January 2018 in “bioRxiv (Cold Spring Harbor Laboratory)” Researchers found key regions in the mouse hairless gene that control its activity in skin and brain cells, affecting hair follicle function.
118 citations,
October 2013 in “Trends in Genetics” The AUTS2 gene is linked to neurological disorders and may affect human brain development and cognition.
51 citations,
November 2011 in “British Journal of Dermatology” A gene called HDAC9 might be a new factor in male-pattern baldness.
13 citations,
June 2020 in “BMC genomics” A specific microRNA, chi-miR-30b-5p, slows down the growth of hair-related cells by affecting the CaMKIIδ gene in cashmere goats.
4 citations,
January 2017 in “Development” Estrogen is important for keeping adult mouse nipple skin healthy by controlling certain cell signals.
2 citations,
September 2022 in “Frontiers in veterinary science” Certain long non-coding RNAs are important for the growth of hair follicles in Inner Mongolian cashmere goats.
82 citations,
August 2006 in “Pharmacology, Biochemistry and Behavior” Certain steroids in the brain affect mood and symptoms of depression, and treatments targeting these steroids show promise for improving these symptoms.
12 citations,
January 2014 in “Cell structure and function” Different combinations of human hair keratins affect how hair fibers form.
4 citations,
August 2020 in “Journal of proteomics” Hair protein composition is similar across different races and shapes.
60 citations,
July 2014 in “Autophagy” The protein FLCN is involved in cellular cleanup and is regulated by ULK1.
32 citations,
July 2018 in “FEBS letters” A specific protein complex increases the activity of a plant enzyme, but this action is not required for plant root hair growth.
25 citations,
July 2016 in “Molecular biology of the cell” A protein in plants needs to bind two lipids to help with root hair growth, and this process is similar across different plant species.
19 citations,
July 2020 in “EBioMedicine” A gene variant increases the risk of a type of hair loss by affecting hair protein production.
7 citations,
February 2023 in “Inflammation and Regeneration” The protein interleukin-1 alpha helps regenerate hair follicles and increase stem cell growth in mice.
3 citations,
March 2023 in “International journal of molecular sciences” Keratin protein production in cells is controlled by a complex system that changes with cell type, health, and conditions like injury or cancer.
2 citations,
November 2022 in “BioMed Research International” Baicalin may help treat hair loss by promoting hair follicle growth and activating specific cellular pathways.
5 citations,
October 2022 in “BMC genomics” Certain microRNAs are important for sheep hair follicle development and could help improve wool quality.
3 citations,
March 2023 in “Biology” Genes affecting wool fiber thickness in Angora rabbits were identified, which could help breed finer wool.
7 citations,
June 2022 in “Frontiers in Veterinary Science” Researchers found genes linked to hair growth cycles in Inner Mongolia cashmere goats, which could help understand and treat hair loss.
5 citations,
May 2021 in “EMBO journal” Cell polarity signaling controls tissue mechanics and cell fate, with complex interactions and varying pathways across species.
March 2024 in “BMC cancer” High levels of ST14 and TMEFF1 proteins in ovarian cancer are linked to worse patient outcomes and may be a new treatment target.
1 citations,
November 2023 in “BMC chemistry” Tadalafil and Finasteride may help treat aggressive melanoma.
1 citations,
July 2023 in “Chinese Medicine” Shi-Bi-Man, a Traditional Chinese Medicine, helps grow hair by boosting lactic acid metabolism and activating hair follicle stem cells.
489 citations,
November 2021 in “Signal Transduction and Targeted Therapy” The JAK/STAT pathway is important in cell processes and disease, and JAK inhibitors are promising for treating related conditions.