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This study found that hair membrane fluidity is low in the cuticle but high in the cortex and medulla, with treatments like ionic surfactants and oleic acid increasing fluidity in hydrated hair; however, dehydration significantly reduces fluidity throughout the hair.

Keratin proteins in epithelial cells are dynamic and crucial for cell processes and disease understanding.

This study's simulations suggest that replenishing free 18‐MEA could restore damaged hair surface properties, highlighting the importance of optimal fatty acid spacing for maintaining hair integrity.

This study explored a cell-free therapy with mesenchymal stem cell paracrine proteins and PEG hydrogels for deep burn treatment and found that the combination significantly enhanced wound healing, reduced scar formation, and promoted skin appendage regeneration in a rabbit model.

This study found that cellular retinoic acid-binding proteins and fatty acid-binding proteins are dynamically expressed in skin development and respond differently to retinoic acid, β-catenin, and Notch signaling.

This study developed a mathematical model indicating that the amino acid sequences of intermediate filament proteins, rather than flexibility differences, significantly impact assembly rates.

This review highlights the potential of peptide-based PROTACs (pPROTACs) in expanding the target range of protein degraders beyond small-molecule limitations, particularly for undruggable proteins, by utilizing advances in design, conjugation, and bioPROTAC technology.

In this in silico study, researchers analyzed nonsynonymous SNPs in the LIPH gene linked to hypotrichosis and identified three potentially harmful variants (W108R, C246S, and H248N) out of 215 total, using sequence- and architecture-based bioinformatics techniques to differentiate between harmful and benign SNPs.

In this study, using tyrosine as a cross-linking agent for hair perming showed better initial results compared to commercial products, though efficiency decreased after washing without compromising hair strength.

This review discusses the potential role of extracellular vesicles in modulating hair follicle dynamics and reports no new clinical results; future investigations may inform treatment strategies for skin disorders.

In this study, researchers found that synchronization between expanding epithelial cells and background mesenchymal cells in the mouse hair cycle may be maintained by inhibitory regulation, with potential mediators of this regulation identified.

This study used molecular dynamics simulations to illustrate the complex molecular behavior of the hair surface F-layer, highlighting how fatty acids interact with 18-MEA under different conditions.

This study found that the protein p63 requires morphogenetic signals to regulate gene expression effectively during skin cell differentiation, highlighting its complex role in therapeutic reprogramming for conditions like epidermolysis bullosa.

This review discusses recent findings on hair follicle morphogenesis and regeneration, focusing on molecular signals and stem cells, and suggests that understanding these processes may aid in developing new strategies for wound healing.

This review discusses immunohistological and immunofluorescent methods for studying the human hair follicle cell cycle, reporting no new results, and suggests its potential for advancing cell cycle research.

This study found that root hairs of wild-type Arabidopsis grow faster and longer under low potassium stress, with changes in actin filament dynamics and specific regulation by the actin bundling proteins VLN1 and VLN4.

In this study, researchers found that simple hair clipping in mice induced dynamic plasticity and axogenesis in skin sensory axons, linked to follicular activation and HGF signaling.

This study found that applying BMP2 stimulated limited regeneration of the amputated P2 bone in mice, but only when applied during a specific "regeneration window" after injury.

This review describes bioengineering strategies to mimic the natural cell microenvironment in vitro, emphasizing the novel approach of using cell-synthesized extracellular matrix as a scaffold for engineering functional 3D tissues, while highlighting the limitations of exogenous scaffolds in tissue engineering.

This study reviews the regulatory mechanisms and molecular processes governing stem cell activity in hair follicles, highlighting their roles in hair regeneration and potential implications for treating hair and skin disorders.

This study introduces a new multimodal imaging technology to visualize and quantify cell dynamics in natural skin over long durations, demonstrated in GFP bone marrow-transplanted mice, to study dynamic skin regeneration.

This article reviews how stem cell exhaustion contributes to aging, emphasizing the balance between proliferation and quiescence as crucial for long-term stem cell maintenance, but it reports no new results.

This study suggests that caribine may enhance the interaction between CRFR and maltose binding protein, potentially offering a new approach for treating hair loss.

This study developed a multiscale model to understand human hair fiber mechanics and found that the yield stress decreases linearly with temperature, supported by both simulations and experimental stretching of hair fibers.

This study identified key genes linked to immune cells and potential therapeutic compounds for alopecia areata by evaluating upregulated genes from patient datasets, highlighting T and NK cell involvement in hair follicle attack and suggesting drug candidates through molecular docking and dynamics simulations.

This study found that the FER/MLO signaling module plays a crucial role in calcium oscillations and ROS production in root hair tip growth, with the MLO15 protein regulating these processes and restoring disrupted growth and signaling in fer mutant root hairs.

This article reviews the generation of complex integument patterns through genetic, chemical, and environmental influences, with applications in tissue engineering, but reports no new experimental results.

In this study, researchers found that a scallop adhesive protein (Sbp9 Δ) forms strong adhesive coatings via disulfide-sticker strategies, which also promote hair regeneration in mouse models by activating Wnt signaling and enhancing angiogenesis, proving more effective than minoxidil for androgenetic alopecia.

This study utilized the DNP–SANS technique on human hair for the first time and found significant changes in the SANS profile dependent on polarization conditions, providing insights into the structural composition and dynamic properties of keratin and its associated proteins.

This study used molecular dynamics simulations to model the outer surface of human hair, illustrating complex behavior and potential adsorption interactions with fatty acids, which may inform cosmetic formulation development.